2-(3-Chlorobenzyl)-4-((2,4-dichlorobenzyl)oxy)quinazoline CAS 861208-37-9
| CAS No. | 861208-37-9 |
| Molecular Formula | C22H15Cl3N2O |
| Molecular Weight | 429.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(3-Chlorobenzyl)-4-((2,4-dichlorobenzyl)oxy)quinazoline (C22H15Cl3N2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-(3-Chlorobenzyl)-4-((2,4-dichlorobenzyl)oxy)quinazoline (CAS 861208-37-9) is a high-purity analytical reference standard with the molecular formula C22H15Cl3N2O and a molecular weight of 429.73 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H15Cl3N2O |
| Molecular Weight | 429.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorobenzyl Standards
- 5-(2-Chlorobenzyl)-7-(3,4-dimethoxyphenyl)-2-methylthiazolo[4,5-d]pyridazin-4(5H)-one (CAS 941949-93-5)
- 3-((4-Chlorobenzyl)thio)-4-ethyl-5-((3-(trifluoromethyl)phenoxy)methyl)-4H-1,2,4-triazole (CAS 383146-70-1)
- 2-(4-Chlorobenzyl)-N-(3-(trifluoromethyl)benzyl)quinazolin-4-amine (CAS 303149-92-0)
- 5-(4-((2-Chlorobenzyl)oxy)-3-iodophenyl)-1,3,4-oxadiazol-2-amine (CAS 1706445-19-3)
- 5-(4-((4-Chlorobenzyl)oxy)-3-iodophenyl)-1,3,4-oxadiazol-2-amine (CAS 1706445-23-9)
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- 1,3-Bis(4-chlorobenzyl)-2-(4-methoxyphenyl)imidazolidine (CAS 5428-35-3)
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Recommended Standards
- (3E)-3-[(4-Chlorophenyl)imino]-1-[(2,6-dichlorophenyl)methyl]-5-methyl-2,3-dihydro-1H-indol-2-one (CAS 478043-07-1)
- 2-[(3-Chlorophenyl)methyl]-4-[(2,6-dichlorophenyl)methoxy]quinazoline (CAS 400078-64-0)
- 326495-40-3 (2R)-2,3-Bis[(~2~H_35_)octadecanoyloxy]propyl 2-{tris[(~2~H_3_)methyl]azaniumyl}(~2~H_4_)ethyl phosphate DTXSID20677036 (CAS 326495-40-3)
- 7,9-Dichloro-5-(4-chlorophenyl)-2-phenyl-5,10b-dihydro-1H-benzo[e]pyrazolo[1,5-c][1,3]oxazine (CAS 302913-77-5)
- 3-Bromo-4-fluoropicolinic acid (CAS 1211540-96-3)
- tert-Butyl n-[cyano(cyclohexyl)methyl]carbamate (CAS 774225-56-8)
- 6-Fluoro-2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 1227210-37-8)
- ((2R,3S,4S,5R,6R)-3,4,5,6-Tetrahydroxytetrahydro-2H-pyran-2-yl)methyl dihydrogen phosphate, sodium salt (CAS 84332-92-3)
- Methyl 2-[5-(2-Chloroacetyl)thiophen-2-yl]acetate (CAS 851340-07-3)
- 4-Bromo-3,5-dimethylbenzonitrile (CAS 75344-77-3)
- Methyl 4-(2-((4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamido)benzoate (CAS 482639-72-5)
- Metronidazole Impurity 26 (CAS 20729-41-3)
- Methyl 5-amino-4,4-difluoropentanoate hydrochloride (CAS 911634-74-7)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
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