2-[(3-Chlorophenyl)methyl]-4-[(2,6-dichlorophenyl)methoxy]quinazoline CAS 400078-64-0
| CAS No. | 400078-64-0 |
| Molecular Formula | C22H15Cl3N2O |
| Molecular Weight | 429.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[(3-Chlorophenyl)methyl]-4-[(2,6-dichlorophenyl)methoxy]quinazoline.
CATO supplies 2-[(3-Chlorophenyl)methyl]-4-[(2,6-dichlorophenyl)methoxy]quinazoline (CAS 400078-64-0), a certified reference material (molecular formula C22H15Cl3N2O, MW 429.73 g/mol) for analytical method development and quality control.
2-[(3-Chlorophenyl)methyl]-4-[(2,6-dichlorophenyl)methoxy]quinazoline (C22H15Cl3N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-[(3-Chlorophenyl)methyl]-4-[(2,6-dichlorophenyl)methoxy]quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H15Cl3N2O |
| Molecular Weight | 429.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- (3E)-3-[(4-Chlorophenyl)imino]-1-[(2,6-dichlorophenyl)methyl]-5-methyl-2,3-dihydro-1H-indol-2-one (CAS 478043-07-1)
- 2-((3-Chlorophenyl)thio)-N-(4-(2,4-dichlorophenyl)thiazol-2-yl)acetamide (CAS 338957-91-8)
- 2-[(4-Chlorophenyl)sulfanyl]-N-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]acetamide (CAS 338957-93-0)
- N-(4-(2-chlorophenyl)thiazol-2-yl)-2-((2,6-dichlorophenyl)thio)acetamide (CAS 338957-66-7)
- N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-2-[(2,3-dichlorophenyl)sulfanyl]acetamide (CAS 338957-62-3)
- N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-2-[(2,5-dichlorophenyl)sulfanyl]acetamide (CAS 338959-63-0)
- Methyl 4-[(2-{[(4-chlorophenyl)carbamoyl]amino}-4-(trifluoromethyl)phenyl)amino]butanoate (CAS 339101-65-4)
- N-(3-Chlorophenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775338-32-3)
Recommended Standards
- 2-(3-Chlorobenzyl)-4-((2,4-dichlorobenzyl)oxy)quinazoline (CAS 861208-37-9)
- 7,9-Dichloro-5-(4-chlorophenyl)-2-phenyl-5,10b-dihydro-1H-benzo[e]pyrazolo[1,5-c][1,3]oxazine (CAS 302913-77-5)
- 7-Chloro-3-(2,4-dichloro-5-isopropoxyphenyl)-2-(methylthio)quinazolin-4(3H)-one (CAS 339099-18-2)
- 326495-40-3 (2R)-2,3-Bis[(~2~H_35_)octadecanoyloxy]propyl 2-{tris[(~2~H_3_)methyl]azaniumyl}(~2~H_4_)ethyl phosphate DTXSID20677036 (CAS 326495-40-3)
- (Deamino-Cys1,β-cyclohexyl-Ala4,Arg8)-Vasopressin (CAS 500170-27-4)
- 1-(4-Chlorobenzyl)-1H-benzimidazole-2-carbaldehyde (CAS 537010-34-7)
- methyl[1-(2-methylphenyl)propan-2-yl]amine hydrochloride (CAS 1645472-48-5)
- 3-amino-5,6-dimethyl-1,2,4-triazine (CAS 17584-12-2)
- Methyl 7-(4-hydroxyphenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate (CAS 329796-06-7)
- 6-Fluoro-2-phenyl-4H-chromen-4-one (CAS 1218-82-2)
- 6-aminospiro[3.3]heptan-2-ol;hydrochloride (CAS 1820979-19-8)
- 3-[(3-Methoxypropyl)amino]propanamide (CAS 1040687-85-1)
- 4-Bromobenzoyl cyanide (CAS 6048-21-1)
- Palmitoyl hexapeptide-6 (CAS 891498-01-4)
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