1-{[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl}-4-(2-fluorophenyl)piperazine CAS 861212-36-4
| CAS No. | 861212-36-4 |
| Molecular Formula | C24H21Cl2FN4 |
| Molecular Weight | 455.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 1-{[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl}-4-(2-fluorophenyl)piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 1-{[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl}-4-(2-fluorophenyl)piperazine (CAS 861212-36-4), a certified reference material (molecular formula C24H21Cl2FN4, MW 455.35 g/mol) for analytical method development and quality control.
The molecular framework of 1-{[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl}-4-(2-fluorophenyl)piperazine (C24H21Cl2FN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C24H21Cl2FN4 |
| Molecular Weight | 455.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
- (2R,3R,4R,5R)-2-[(4-chlorobenzoyloxy)methyl]-4-fluoro-5-hydroxy-4-methyloxolan-3-yl 4-chlorobenzoate (CAS 1294481-80-3)
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- Budesonide Impurity 38 (CAS CATO-C4X-138938)
- Ethyl 2-((4-(3-(4,5-dichloro-2-methylphenyl)-4,5-dihydro-1H-pyrazol-1-yl)phenyl)sulfonyl)acetate (CAS 35441-14-6)
- 1H-Purine-6-sulfonic acid (CAS 25023-39-6)
- 2-(4-Chlorophenoxy)-3-[3-(trifluoromethyl)phenyl]quinoline (CAS 337921-84-3)
- 2-(3-Ethyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-1-yl)ethanamine (CAS 1539241-82-1)
- 10-Ethyl-10H-phenoxazine-3-carboxylic acid (CAS 108536-35-2)
- 1-Bromo-4-(2,2-difluorovinyl)benzene (CAS 84750-93-6)
- 3-Bromo-5-methoxy-pyridin-2-amine (CAS 1379325-16-2)
- 1-(4-(5-Methylthiophen-2-yl)thiazol-2-yl)ethan-1-amine (CAS 642931-50-8)
- N2,N6-Dibenzyl-4-(trifluoromethyl)pyridine-2,6-dicarboxamide (CAS 1210304-46-3)
- 6-Iodo-4-methyl-1H-indazole-3-carboxylic acid (CAS 885521-24-4)
- D-Lys16-Tirzepatide (CAS CATO-CPTD788918)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com