N-(3-chloro-4-methylphenyl)-2-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)acetamide CAS 866017-70-1
| CAS No. | 866017-70-1 |
| Molecular Formula | C21H15Cl2F3N2O2 |
| Molecular Weight | 455.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(3-chloro-4-methylphenyl)-2-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)acetamide (CAS 866017-70-1), molecular formula C21H15Cl2F3N2O2 and molecular weight 455.26 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N-(3-chloro-4-methylphenyl)-2-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)acetamide (C21H15Cl2F3N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 455.26 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H15Cl2F3N2O2 |
| Molecular Weight | 455.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- N-(4-chloro-2-methylphenyl)-2-(N-(2-chloro-5-(trifluoromethyl)phenyl)methylsulfonamido)acetamide (CAS 339018-85-8)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-1-[(4-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 338399-22-7)
- 1-{[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl}-4-(2-fluorophenyl)piperazine (CAS 861212-36-4)
- 4-Chloro-N-(1-(4-ethyl-5-((3-fluorobenzyl)thio)-4H-1,2,4-triazol-3-yl)ethyl)benzenesulfonamide (CAS 338954-01-1)
- 2-(4-(5-Chloro-2-methylphenyl)piperazin-1-yl)-7-(3-fluorophenyl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1251599-14-0)
- 1-({5-(6-chloro-3-pyridyl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}thio)-3,3-dimethylbutan-2-one (CAS 680217-04-3)
- 2-Chloro-1,5-bis(m-tolyloxy)anthracene-9,10-dione (CAS 61601-43-2)
- 2-Chloro-1,8-bis(m-tolyloxy)anthracene-9,10-dione (CAS 61601-44-3)
Recommended Standards
- Resmetirom Impurity 51 (CAS CATO-C4X-291251)
- Roxadustat Impurity 140 (CAS CATO-C4X-2213140)
- (2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(2-bromoethoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 16977-78-9)
- N-((4-fluorobenzoyl)oxy)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 320418-84-6)
- 5-Bromo-2-iodo-1,3-dimethylbenzene (CAS 260355-37-1)
- 1-(5-(4-Benzylpiperazin-1-yl)-1,3,4-thiadiazol-2-yl)-1H-pyrrole-2-carbaldehyde (CAS 1242988-39-1)
- Zotepine N-Oxide (CAS 63720-83-2)
- 5-Chloro-3-methyl-4-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole (CAS 2265200-73-3)
- 11-Acetylmercaptoundecylphosphonic acid (CAS 304012-57-5)
- 1,3-Dimethyl-4-phenyl-1H-pyrazol-5(4H)-one (CAS 1706-41-8)
- Methyl pentafluorobut-3-enoate (CAS 20562-79-2)
- (3-Amino-6-(pyridin-3-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carbonyl)glycine (CAS 899370-08-2)
- Tert-butyl (S)-(2-(hydroxymethyl)pentyl)carbamate (CAS 896721-72-5)
- [His]1+12-Semaglutide (CAS CATO-C4X-2226178)
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