(4-Cyano-3,5-difluorophenyl)boronic acid CAS 861710-03-4
| CAS No. | 861710-03-4 |
| Molecular Formula | C7H4BF2NO2 |
| Molecular Weight | 182.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (4-Cyano-3,5-difluorophenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(4-Cyano-3,5-difluorophenyl)boronic acid (CAS 861710-03-4) is a high-purity analytical reference standard with the molecular formula C7H4BF2NO2 and a molecular weight of 182.92 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, (4-Cyano-3,5-difluorophenyl)boronic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 182.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H4BF2NO2 |
| Molecular Weight | 182.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Cyano Standards
- (2-Cyano-3,6-difluorophenyl)boronic acid (CAS 1357163-26-8)
- (4-cyano-2,5-difluorophenyl)boronic acid (CAS 1628442-75-0)
- (2-Cyano-4,5-difluorophenyl)boronic acid (CAS 2199440-55-4)
- (3-Cyano-4,5-difluorophenyl)boronic acid (CAS 2199440-57-6)
- 4-Cyano-2,3-difluorophenylboronic acid (CAS 2377608-51-8)
- 4-Cyano-2,6-difluorophenylboronic acid (CAS 2199440-52-1)
- (3-CYANO-2,4-DIFLUOROPHENYL)BORONIC ACID 2,4-DIFLUORO-3-CYANOPHENYLBORONIC ACID 871940-31-7 BC001248 BORONIC ACID, B-(3-CYANO-2,4-DIFLUOROPHENYL)- (CAS 871940-31-7)
- (2-Cyano-2-(ethoxycarbonyl)cyclopropyl)boronic acid (CAS 2225153-58-0)
Recommended Standards
- (3-Hydroxy-5-nitrophenyl)boronic acid (CAS 737001-07-9)
- 2-[8-(1,4-Dioxa-8-azaspiro[4.5]decyl)methyl]phenylmagnesium bromide 0.25 M in Tetrahydrofuran (CAS 1187164-30-2)
- (4-Hydroxy-3-nitrophenyl)boronic acid (CAS 850568-75-1)
- Tin(iv) sulfide (CAS 1315-01-1)
- Nickel(II) stearate (CAS 2223-95-2)
- 2-(Methylsulfanyl)-3-nitro-5-(trifluoromethyl)pyridine (CAS 1881332-03-1)
- 4-((Tetrahydrofuran-2-yl)methoxy)piperidine (CAS 883537-64-2)
- 10-Benzyl-9,10-dihydroacridine (CAS 87742-33-4)
- 9-Ethyl-9H-carbazole-2-carbaldehyde (CAS 56166-62-2)
- 5-Nitro-1,2-benzisoxazole (CAS 39835-28-4)
- 4,6-Dimethyl-1,2,3-triazine (CAS 77202-09-6)
- (4-(4-(p-Tolyl)thiazol-2-yl)phenyl)methanamine (CAS 951912-74-6)
- Ampicillin Impurity 41 (CAS CATO-C4X-144341)
- Semaglutide impurity 272 (CAS CATO-C4X-2226272)
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