(2E)-1-(4-Bromophenyl)-3-(2-chlorophenyl)prop-2-en-1-one CAS 86293-48-3

Purity 97%+In StockPharmaceutical Standards
CAS No.86293-48-3
Molecular FormulaC15H10BrClO
Molecular Weight321.60 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2E)-1-(4-Bromophenyl)-3-(2-chlorophenyl)prop-2-en-1-one CAS 86293-48-3 chemical structure

Description

CATO supplies (2E)-1-(4-Bromophenyl)-3-(2-chlorophenyl)prop-2-en-1-one (CAS 86293-48-3), a certified reference material (molecular formula C15H10BrClO, MW 321.60 g/mol) for analytical method development and quality control.

The molecular framework of (2E)-1-(4-Bromophenyl)-3-(2-chlorophenyl)prop-2-en-1-one (C15H10BrClO) is characterized by a hydroxyl group, an ether linkage, chlorine/bromine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H10BrClO
Molecular Weight321.60 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1981
Halogen ContentCl/Br-containing

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