Sofosbuvir Impurity 73 CAS 863329-64-0
| CAS No. | 863329-64-0 |
| Molecular Formula | C31H27N3O8 |
| Molecular Weight | 569.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Sofosbuvir Impurity 73 (CAS 863329-64-0) is a certified pharmaceutical impurity reference standard with the molecular formula C31H27N3O8 and a molecular weight of 569.56 g/mol.
Based on its molecular formula C31H27N3O8, Sofosbuvir Impurity 73 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 569.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C31H27N3O8 |
| Molecular Weight | 569.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
Related Sofosbuvir Standards
- Sofosbuvir Impurity 12 (CAS 863329-62-8)
- Sofosbuvir Impurity 77 (CAS CATO-C4X-105277)
- Sofosbuvir Impurity 81 (CAS 23643-36-9)
- Sofosbuvir Impurity 10 (CAS CATO-C4X-105210)
- Sofosbuvir Impurity 11 (CAS CATO-C4X-105211)
- Sofosbuvir Impurity 4 (CAS 874638-94-5)
- Sofosbuvir Impurity 5 (CAS CATO-C4X-10525)
- Sofosbuvir Impurity 6 (CAS CATO-C4X-10526)
Recommended Standards
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