2-(Bromomethyl)-6-chlorobenzonitrile CAS 863676-23-7
| CAS No. | 863676-23-7 |
| Molecular Formula | C8H5BrClN |
| Molecular Weight | 230.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(Bromomethyl)-6-chlorobenzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(Bromomethyl)-6-chlorobenzonitrile (CAS 863676-23-7) is a high-purity analytical reference standard with the molecular formula C8H5BrClN and a molecular weight of 230.49 g/mol.
The molecular framework of 2-(Bromomethyl)-6-chlorobenzonitrile (C8H5BrClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H5BrClN |
| Molecular Weight | 230.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromomethyl Standards
- 3-(Bromomethyl)-5-chlorobenzonitrile (CAS 1021871-36-2)
- 3-(Bromomethyl)-4-chlorobenzonitrile (CAS 1021871-37-3)
- 3-(Bromomethyl)-2-chlorobenzonitrile (CAS 1261499-45-9)
- 2-(Bromomethyl)-3-chlorobenzonitrile (CAS 77533-18-7)
- 2-(Bromomethyl)-4-chlorobenzonitrile (CAS 50712-67-9)
- 4-(Bromomethyl)-2-chlorobenzonitrile (CAS 83311-25-5)
- 4-(Bromomethyl)-3-chlorobenzonitrile (CAS 21924-83-4)
- 5-(Bromomethyl)-2-chlorobenzonitrile (CAS 99613-64-6)
Recommended Standards
- 2-Bromo-2-(4-chlorophenyl)acetonitrile (CAS 53731-99-0)
- 2-Bromo-4-chloro-5-methylbenzonitrile (CAS 2092187-93-2)
- 2-(4-Bromo-2-chlorophenyl)acetonitrile (CAS 67197-54-0)
- 3-Bromo-5-chloro-2-methylbenzonitrile (CAS 939990-01-9)
- 1-(4-Methylphenyl)-2,3,4,9-tetrahydro-1H-beta-carboline hydrochloride (CAS 3380-70-9)
- Methyl 2-(2-chloro-1H-indol-3-yl)acetate (CAS 1912-34-1)
- 2,2,2-trifluoroethyl N-(1,3-oxazol-4-yl)carbamate (CAS 1375472-82-4)
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- (6-(Dipropylamino)pyridin-3-yl)(phenyl)methanone (CAS 1355223-75-4)
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- Chloro[hydrotris(pyrazol-1-yl)borato]bis(triphenylphosphine)ruthenium(II) ethanol adduct (CAS 141686-21-7)
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