Pemetrexed Impurity 43 CAS 863767-87-7
| CAS No. | 863767-87-7 |
| Molecular Formula | C13H16O4 |
| Molecular Weight | 236.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 236.26 g/mol gives Pemetrexed Impurity 43 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Pemetrexed Impurity 43 (CAS 863767-87-7) is a certified pharmaceutical impurity reference standard with the molecular formula C13H16O4 and a molecular weight of 236.26 g/mol.
The molecular framework of Pemetrexed Impurity 43 (C13H16O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Pemetrexed Impurity 43 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H16O4 |
| Molecular Weight | 236.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
Related Pemetrexed Standards
- Pemetrexed Impurity 48 (CAS CATO-C4X-172648)
- Pemetrexed Impurity 62 (CAS 61495-31-6)
- Pemetrexed Impurity 11 (CAS 778-29-0)
- Pemetrexed Impurity 53 (CAS 53487-52-8)
- Pemetrexed Impurity 61 (CAS CATO-C4X-172661)
- Pemetrexed Impurity 41 (CAS 912935-44-5)
- Pemetrexed Impurity 39 (CAS 89113-43-9)
- Pemetrexed Impurity 10 (CAS 151864-81-2)
Recommended Standards
- Amiodarone Impurity 39 (CAS 138320-27-1)
- Bisoprolol Impurity 70 (CAS 84425-10-5)
- Sulbactam-d3 (CAS CATO-C4X-175614)
- (1r,3r,5r,7r)-Spiro[adamantane-2,2'-[1,3]dioxane]-4',6'-dione (CAS 455329-56-3)
- Daptomycin Impurity 47 (CAS CATO-C4X-137847)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
- Drotaverin Impurity 56 (CAS CATO-C4X-243556)
- Methyl 5-Fluoroindole-3-acetate (CAS 497258-29-4)
- (1s,2r)-1-Amino-2-(trifluoromethyl)cyclopropane-1-carboxylic acid hydrochloride (CAS 1955473-52-5)
- 2-Bromo-1-(3-(4-chlorophenyl)-5-methylisoxazol-4-yl)ethan-1-one (CAS 1159981-10-8)
- 2-((6-Chloropyridazin-3-yl)methyl)isoindoline-1,3-dione (CAS 948996-03-0)
- Methyl 5-methoxy-1-methyl-1H-pyrazole-3-carboxylate (CAS 58364-91-3)
- 3-[5-(Piperidin-4-yl)-[1,2,4]-oxadiazol-3-yl]-pyridine (CAS 849925-01-5)
- D-γ-Glu20-Side-Tirzepatide (CAS CATO-CPTD788929)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com