Pemetrexed Impurity 11 CAS 778-29-0
| CAS No. | 778-29-0 |
| Molecular Formula | C11H14O3S |
| Molecular Weight | 226.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 226.29 g/mol gives Pemetrexed Impurity 11 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Pemetrexed Impurity 11 (CAS 778-29-0) is a certified pharmaceutical impurity reference standard with the molecular formula C11H14O3S and a molecular weight of 226.29 g/mol.
The molecular framework of Pemetrexed Impurity 11 (C11H14O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Pemetrexed Impurity 11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H14O3S |
| Molecular Weight | 226.29 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Sulfur Atoms | 1 |
Related Pemetrexed Standards
- Pemetrexed Impurity 53 (CAS 53487-52-8)
- Pemetrexed Impurity 61 (CAS CATO-C4X-172661)
- Pemetrexed Impurity 41 (CAS 912935-44-5)
- Pemetrexed Impurity 43 (CAS 863767-87-7)
- Pemetrexed Impurity 48 (CAS CATO-C4X-172648)
- Pemetrexed Impurity 62 (CAS 61495-31-6)
- Pemetrexed Impurity 39 (CAS 89113-43-9)
- Pemetrexed Impurity 10 (CAS 151864-81-2)
Recommended Standards
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- 9-Fluorofluorene (CAS 20825-90-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com