4-Methoxy-3-(N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)sulfamoyl)benzoic acid CAS 865273-97-8
| CAS No. | 865273-97-8 |
| Molecular Formula | C20H21F3N2O5S |
| Molecular Weight | 458.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Methoxy-3-(N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)sulfamoyl)benzoic acid (CAS 865273-97-8), molecular formula C20H21F3N2O5S and molecular weight 458.45 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Methoxy-3-(N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)sulfamoyl)benzoic acid (C20H21F3N2O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Methoxy-3-(N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)sulfamoyl)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H21F3N2O5S |
| Molecular Weight | 458.45 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methoxy Standards
- 3-Methoxy-2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-ol (CAS 2874309-17-6)
- 3-Methoxy-4-((4-((3-oxo-2,3-dihydro-1H-inden-4-yl)oxy)-5-(trifluoromethyl)pyrimidin-2-yl)amino)benzoic acid (CAS 1227948-58-4)
- (E)-4-methoxy-N-((((4-methylbenzyl)oxy)imino)methyl)-2-(3-(trifluoromethyl)phenoxy)nicotinamide (CAS 478262-36-1)
- Methyl 3-[(2-methoxy-2-oxoethyl)(4-methylphenyl)sulfamoyl]-4-phenylthiophene-2-carboxylate (CAS 1021213-00-2)
- 5-Methoxy-2-((tosyloxy)methyl)tetrahydrofuran-3-yl 4-methylbenzenesulfonate (CAS 60110-72-7)
- 5-((3-(4-Methoxy-3-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-2-morpholinothiazol-4(5H)-one (CAS 623935-37-5)
- 2-((Methoxy(methyl)amino)methylene)-N1,N3-bis(4-(trifluoromethyl)phenyl)malonamide (CAS 337921-18-3)
- 4-Methoxy-N'-(2-(3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazole-4-carbonyl)benzenesulfonohydrazide (CAS 956795-64-5)
Recommended Standards
- (3-Amino-6-(2,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)(phenyl)methanone (CAS 625377-58-4)
- Digalactosyl Diglyceride (CAS 92457-02-8)
- 1-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]-7-hydroxy-3,4-dihydro- carbostyril-d8 (CAS 1794789-13-1)
- Phenyl(3-(((3-(trifluoromethyl)benzyl)sulfonyl)methyl)benzofuran-2-yl)methanone (CAS 866017-29-0)
- 3-(Hydroxymethyl)-5-methoxyphenol (CAS 30891-29-3)
- (Z)-5-(Hydroxymethyl)-3-((4-(morpholinomethyl)-1H-pyrrol-2-yl)methylene)indolin-2-one (CAS 1265965-20-5)
- Ethyl 2-aminothiazolo[4,5-b]pyridine-7-carboxylate (CAS 907545-44-2)
- (1-((4-Fluorophenyl)sulfonyl)piperidine-4-carbonyl)glycine (CAS 929969-80-2)
- 2-(4-(Isopentyloxy)phenyl)ethan-1-ol (CAS 106379-94-6)
- Methyl 3-Hydroxy-5-trifluoromethylthiophene-2-carboxylate (CAS 157162-16-8)
- 2-Chloro-N-(prop-2-yn-1-yl)pyridine-3-sulfonamide (CAS 1155914-37-6)
- Binimetinib Impurity 2 (CAS 391212-29-6)
- Pemetrexed Impurity 50 (CAS CATO-C4X-172650)
- Casein Kinase II Receptor Peptide (CAS 198481-81-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com