2-(4-chloranyl-3-fluoranyl-phenyl)ethanoic acid 2-(4-chloro-3-fluorophenyl)acetic acid 865451-00-9 A841715 CAS 865451-00-9
| CAS No. | 865451-00-9 |
| Molecular Formula | C8H6ClFO2 |
| Molecular Weight | 188.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-chloranyl-3-fluoranyl-phenyl)ethanoic acid 2-(4-chloro-3-fluorophenyl)acetic acid 865451-00-9 A841715.
2-(4-chloranyl-3-fluoranyl-phenyl)ethanoic acid 2-(4-chloro-3-fluorophenyl)acetic acid 865451-00-9 A841715 (CAS 865451-00-9), molecular formula C8H6ClFO2 and molecular weight 188.58 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-chloranyl-3-fluoranyl-phenyl)ethanoic acid 2-(4-chloro-3-fluorophenyl)acetic acid 865451-00-9 A841715 (C8H6ClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-chloranyl-3-fluoranyl-phenyl)ethanoic acid 2-(4-chloro-3-fluorophenyl)acetic acid 865451-00-9 A841715 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6ClFO2 |
| Molecular Weight | 188.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related chloranyl Standards
- 2-chloranyl-5-(trifluoromethyl)pyrimidine 2-chloro-5-(trifluoromethyl)pyrimidine 69034-12-4 A836321 (CAS 69034-12-4)
- 3-chloranyl-4-fluoranyl-benzoyl chloride 3-chloro-4-fluorobenzoyl chloride 65055-17-6 A834956 (CAS 65055-17-6)
- 3-chloranyl-6-pyrrolidin-1-yl-pyridazine 3-chloro-6-(1-pyrrolidinyl)pyridazine 66346-85-8 A835428 (CAS 66346-85-8)
- 2-chloranyl-4-isocyanato-1-methoxy-benzene 2-chloro-4-isocyanato-1-methoxybenzene 28395-76-8 A819435 (CAS 28395-76-8)
- 4-chloranyl-2-isocyanato-1-methoxy-benzene 4-chloro-2-isocyanato-1-methoxybenzene 55440-54-5 A830644 (CAS 55440-54-5)
- 5-chloranyl-2-methoxy-pyridine-3-carboxylic acid 5-chloro-2-methoxy-3-pyridinecarboxylic acid 54916-65-3 A830407 (CAS 54916-65-3)
- 350-92-5 4-chloranyl-3-[chloranyl-bis(fluoranyl)methyl]-4,4-bis(fluoranyl)-1-(furan-2-yl)-3-oxidanyl-butan-1-one 4-chloro-3-[chloro(difluoro)methyl]-4,4-difluoro-1-(2-furanyl)-3-hydroxy-1-butanone A822529 (CAS 350-92-5)
- 252004-45-8 4-chloranyl-2,6-bis(fluoranyl)benzaldehyde 4-chloro-2,6-difluorobenzaldehyde A817702 (CAS 252004-45-8)
Recommended Standards
- 5-Chloro-2-trifluoromethylpyrazine 2-Chloro-5-(trifluoromethyl)pyrazine 799557-87-2 (CAS 799557-87-2)
- 4-Chloro-2-fluorobenzohydrazide (CAS 1016768-00-5)
- 2-Amino-3-chloro-5-fluorobenzamide (CAS 1191420-40-2)
- 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE 33034-67-2 4-(TRIFLUOROMETHYL)-2-CHLOROPYRIMIDINE ABBYPHARMA AP-10-1130 NF10300 PYRIMIDINE, 2-CHLORO-4-(TRIFLUOROMETHYL)- (CAS 33034-67-2)
- 2-((Cyclopropylmethyl)amino)-5-nitrobenzonitrile (CAS 1007826-31-4)
- 937618-77-4 3-[(3-Chloro-5-ethoxy-4-methoxyphenyl)methyl]azetidine DTXSID10588369 (CAS 937618-77-4)
- 4-Isopropylthiazole-5-carbaldehyde (CAS 261710-80-9)
- (R)-2-(1-Aminoethyl)-6-(difluoromethyl)pyridin-4-amine (CAS 2654746-53-7)
- 2-(3-Methylpiperidin-1-yl)-N-(2,4,6-trichlorophenyl)acetamide (CAS 332162-66-0)
- 4,4''-Diformyl-5'-(4-formylphenyl)-N2',N4',N6'-trihexyl-[1,1':3',1''-terphenyl]-2',4',6'-tricarboxamide (CAS 2413680-71-2)
- 1-(4-Bromophenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrazole-5-carboxylic acid (CAS 618383-03-2)
- 5-Cyclobutylpyrrolidine-2-carboxylic acid (CAS 1270315-55-3)
- N-(2-(2-phenyl-1H-indol-3-yl)ethyl)acetamide (CAS 4560-07-0)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com