n-(5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide CAS 865660-10-2
| CAS No. | 865660-10-2 |
| Molecular Formula | C12H8F3N3O3S |
| Molecular Weight | 331.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including n-(5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide.
CATO supplies n-(5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide (CAS 865660-10-2), a certified reference material (molecular formula C12H8F3N3O3S, MW 331.27 g/mol) for analytical method development and quality control.
Based on its molecular formula C12H8F3N3O3S, n-(5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 331.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), n-(5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8F3N3O3S |
| Molecular Weight | 331.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related n Standards
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- 2,2'-(4-(Trifluoromethyl)pyridine-2,6-diyl)diphenol (CAS 603131-01-7)
- 3'-Phenyl-2-(trifluoromethyl)-4'H-spiro[chromene-4,5'-isoxazole] (CAS 784144-78-1)
- 3-Phenyl-4-({[3-(trifluoromethyl)phenyl]amino}methylidene)-4,5-dihydro-1H-pyrazol-5-one (CAS 338975-63-6)
- 3-Phenyl-4-({[4-(trifluoromethyl)phenyl]amino}methylidene)-4,5-dihydro-1H-pyrazol-5-one (CAS 477851-10-8)
- methyl 4-(2-(4-(trifluoromethyl)piperidin-1-yl)ethoxy)benzoate (CAS 1000339-87-6)
- 5-((3-(Trifluoromethyl)phenyl)amino)-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one (CAS 1020252-08-7)
- 4-(3,5-Bis(trifluoromethyl)phenoxy)benzonitrile (CAS 243128-43-0)
Recommended Standards
- 6-Fluoro-1-(2-fluoroethyl)-4-oxo-7-(pyridin-4-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid (CAS 99108-92-6)
- Tert-butyl 2-((4-bromophenyl)thio)-2-methylpropanoate (CAS 247923-30-4)
- 5-Bromo-N-(1-propylpiperidin-4-yl)thiophene-2-carboxamide (CAS 945139-42-4)
- Dabrafenib Impurity 20 (CAS CATO-C4X-303320)
- 6-(bromomethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 126401-89-6)
- methyl thieno[2,3-c]pyridine-5-carboxylate (CAS 253332-81-9)
- 4-(Difluoromethyl)pyridin-3-amine (CAS 1554366-06-1)
- 2-[2-(1,3-diketoisoindolin-2-yl)ethyl]isoindoline-1,3-quinone (CAS 607-26-1)
- 1-(Benzo[d][1,3]dioxol-5-yl)pentan-1-one (CAS 63740-98-7)
- 1-(2-Amino-5-methylphenyl)-2-(pyrrolidin-1-yl)ethanone (CAS 791015-18-4)
- 5,6,7,8-Tetrahydroindolizin-7-amine (CAS 1369145-01-6)
- 3-(Pyrrolidin-2-yl)-1,2,3,4-tetrahydroquinoline (CAS 912771-32-5)
- 1-(4-Fluorophenyl)-3-phenyl-1h-pyrazol-5-amine (CAS 72411-51-9)
- Semaglutide Impurity 190 (CAS CATO-C4X-2226190)
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