2-Chloro-5-((3-methyl-4-(m-tolyl)piperazin-1-yl)methyl)thiazole CAS 865660-20-4
| CAS No. | 865660-20-4 |
| Molecular Formula | C16H20ClN3S |
| Molecular Weight | 321.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-5-((3-methyl-4-(m-tolyl)piperazin-1-yl)methyl)thiazole is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Chloro-5-((3-methyl-4-(m-tolyl)piperazin-1-yl)methyl)thiazole (CAS 865660-20-4), molecular formula C16H20ClN3S and molecular weight 321.87 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-5-((3-methyl-4-(m-tolyl)piperazin-1-yl)methyl)thiazole (C16H20ClN3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H20ClN3S |
| Molecular Weight | 321.87 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-Chloro-5,6,7,8-tetrahydro-2-(1-piperidinylmethyl)[1]benzothieno[2,3-d]pyrimidine (CAS 731827-03-5)
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Recommended Standards
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