(E)-2-phenyl-4-(((4-(thiophen-2-yl)pyrimidin-2-yl)amino)methylene)oxazol-5(4H)-one CAS 865660-34-0

Purity 97%+In StockPharmaceutical Standards
CAS No.865660-34-0
Molecular FormulaC18H12N4O2S
Molecular Weight348.38 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-2-phenyl-4-(((4-(thiophen-2-yl)pyrimidin-2-yl)amino)methylene)oxazol-5(4H)-one CAS 865660-34-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-2-phenyl-4-(((4-(thiophen-2-yl)pyrimidin-2-yl)amino)methylene)oxazol-5(4H)-one.

CATO supplies (E)-2-phenyl-4-(((4-(thiophen-2-yl)pyrimidin-2-yl)amino)methylene)oxazol-5(4H)-one (CAS 865660-34-0), a certified reference material (molecular formula C18H12N4O2S, MW 348.38 g/mol) for analytical method development and quality control.

The molecular framework of (E)-2-phenyl-4-(((4-(thiophen-2-yl)pyrimidin-2-yl)amino)methylene)oxazol-5(4H)-one (C18H12N4O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (E)-2-phenyl-4-(((4-(thiophen-2-yl)pyrimidin-2-yl)amino)methylene)oxazol-5(4H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC18H12N4O2S
Molecular Weight348.38 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Nitrogen Atoms4
Sulfur Atoms1

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