N-(5-(tert-butyl)-1,3,4-thiadiazol-2-yl)-2-chloronicotinamide CAS 866010-66-4

Purity 97%+In StockPharmaceutical Standards
CAS No.866010-66-4
Molecular FormulaC12H13ClN4OS
Molecular Weight296.78 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(5-(tert-butyl)-1,3,4-thiadiazol-2-yl)-2-chloronicotinamide CAS 866010-66-4 chemical structure

Description

N-(5-(tert-butyl)-1,3,4-thiadiazol-2-yl)-2-chloronicotinamide (CAS 866010-66-4) is a high-purity analytical reference standard with the molecular formula C12H13ClN4OS and a molecular weight of 296.78 g/mol.

The molecular framework of N-(5-(tert-butyl)-1,3,4-thiadiazol-2-yl)-2-chloronicotinamide (C12H13ClN4OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures N-(5-(tert-butyl)-1,3,4-thiadiazol-2-yl)-2-chloronicotinamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H13ClN4OS
Molecular Weight296.78 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms4
Sulfur Atoms1

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