| CAS No. | 866010-67-5 |
| Molecular Formula | C12H13ClN4OS |
| Molecular Weight | 296.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 296.78 g/mol gives N-(5-(tert-butyl)-1,3,4-thiadiazol-2-yl)-6-chloronicotinamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies N-(5-(tert-butyl)-1,3,4-thiadiazol-2-yl)-6-chloronicotinamide (CAS 866010-67-5), a certified reference material (molecular formula C12H13ClN4OS, MW 296.78 g/mol) for analytical method development and quality control.
The molecular framework of N-(5-(tert-butyl)-1,3,4-thiadiazol-2-yl)-6-chloronicotinamide (C12H13ClN4OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(5-(tert-butyl)-1,3,4-thiadiazol-2-yl)-6-chloronicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C12H13ClN4OS |
| Molecular Weight | 296.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |