N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-2,6-dichloropyridine-3-carboxamide CAS 866010-68-6
| CAS No. | 866010-68-6 |
| Molecular Formula | C12H12Cl2N4OS |
| Molecular Weight | 331.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 331.22 g/mol gives N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-2,6-dichloropyridine-3-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-2,6-dichloropyridine-3-carboxamide (CAS 866010-68-6), molecular formula C12H12Cl2N4OS and molecular weight 331.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-2,6-dichloropyridine-3-carboxamide (C12H12Cl2N4OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-2,6-dichloropyridine-3-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12Cl2N4OS |
| Molecular Weight | 331.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Recommended Standards
- Ethyl 2-((3,5-dichlorophenyl)amino)-4-methylthiazole-5-carboxylate (CAS 432501-53-6)
- 2’-Deoxyadenosine 5’-Monophosphate (CAS 653-63-4)
- Ethyl 2-((2,5-dichlorophenyl)amino)-4-methylthiazole-5-carboxylate (CAS 886499-26-9)
- N-(4-Bromophenyl)-4-phenylthiazol-2-amine (CAS 108237-91-8)
- 4-(3-(2,4-Dimethylphenyl)-3-oxoprop-1-en-1-yl)phenyl thiophene-2-carboxylate (CAS 331460-50-5)
- 2-[(dimethylamino)(methylsulfanyl)methylidene]propanedinitrile (CAS 31297-60-6)
- 4-Hydrazinyl-3-methylpyridine (CAS 114913-51-8)
- 1-{[4-(trifluoromethyl)phenyl]methyl}cyclopropan-1-amine (CAS 778-16-5)
- Safinamide Impurity 8 (CAS 202825-45-4)
- 1-(4-Chlorobenzenesulfonyl)-N'-[(1E)-(4-methylphenyl)methylidene]piperidine-4-carbohydrazide (CAS 478030-74-9)
- 2-Bromo-4,6-difluorobenzenethiol (CAS 1208076-63-4)
- Methyl 3-((4-methoxyphenyl)carbamoyl)isonicotinate (CAS 339101-51-8)
- 2-Amino-3-(4-methyl-3-oxo-2,3-dihydroisoxazol-5-yl)propanoic acid (CAS 77006-29-2)
- Peptide 435 (CAS CATO-CPTD788435)
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