1-(3-Cyano-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrol-2-yl)-3-(3-(trifluoromethyl)phenyl)urea CAS 866017-62-1
| CAS No. | 866017-62-1 |
| Molecular Formula | C23H21F3N4O2 |
| Molecular Weight | 442.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 442.43 g/mol gives 1-(3-Cyano-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrol-2-yl)-3-(3-(trifluoromethyl)phenyl)urea distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-(3-Cyano-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrol-2-yl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 866017-62-1), a certified reference material (molecular formula C23H21F3N4O2, MW 442.43 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-(3-Cyano-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrol-2-yl)-3-(3-(trifluoromethyl)phenyl)urea is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 442.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(3-Cyano-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrol-2-yl)-3-(3-(trifluoromethyl)phenyl)urea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H21F3N4O2 |
| Molecular Weight | 442.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Cyano Standards
- Ethyl 5-cyano-2-phenyl-6-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyridine-3-carboxylate (CAS 306980-09-6)
- 3-{3-cyano-1-[(4-methoxyphenyl)methyl]-4,5-dimethyl-1H-pyrrol-2-yl}-1-(3,4-dichlorophenyl)urea (CAS 866038-94-0)
- Ethyl 5-cyano-6-{[(2,4-dichlorophenyl)methyl]sulfanyl}-2-phenylpyridine-3-carboxylate (CAS 306980-11-0)
- N-(2-Cyano-3-methylbutan-2-yl)-2-((4-(2,4-difluorophenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 745068-65-9)
- N-(2-Cyano-3-methylbutan-2-yl)-2-((5,6-dimethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 761420-54-6)
- Ethyl 2-((3-cyano-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)pyridin-2-yl)thio)propanoate (CAS 497246-11-4)
- N-(3-cyano-4-((3-(trifluoromethyl)phenyl)sulfinyl)phenyl)-3-methoxybenzamide (CAS 477710-04-6)
- Ethyl 2-(2-cyano-3-(4-isopropylphenyl)acrylamido)-5-phenylthiophene-3-carboxylate (CAS 469872-53-5)
Recommended Standards
- (S)-WSD0922 (CAS 2226552-65-2)
- N-(4-Fluorophenyl)-4-{4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}benzamide (CAS 338396-99-9)
- N-(4-Phenoxyphenyl)-1-[6-(trifluoromethyl)pyrimidin-4-yl]piperidine-4-carboxamide (CAS 1775546-75-2)
- Ruxolitinib Impurity 54 (CAS CATO-C4X-205854)
- (E)-N'-(3-Cyano-4-methoxypyridin-2-yl)-N,N-dimethylmethanimidamide (CAS 338412-35-4)
- H-Gly-Cys-OH (CAS 57281-78-4)
- 2-(4-Methoxyphenyl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one (CAS 63384-41-8)
- 2-(Methylamino)-1-(3-methylphenyl)ethan-1-ol (CAS 1017480-53-3)
- 5-Methyl-1-(pyridin-2-yl)-1H-pyrazole-4-sulfonamide (CAS 1248684-41-4)
- 5-Bromo-6-isopropylpyridin-3-amine (CAS 1779960-28-9)
- 2-Bromo-3-methoxycyclohex-2-en-1-one (CAS 85493-96-5)
- N-Hydroxydecanimidamide (CAS 88542-64-7)
- 3-Amino-2,2-dimethyl-1-(piperidin-1-yl)propan-1-one (CAS 1249357-47-8)
- Neuroendocrine Regulatory Peptide-4 (human, mouse, rat) (H-7266.1000) (CAS 922704-18-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com