4-Methoxy-N-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methyl)benzamide CAS 866018-74-8
| CAS No. | 866018-74-8 |
| Molecular Formula | C20H17F3N2O2S |
| Molecular Weight | 406.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Methoxy-N-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methyl)benzamide.
CATO supplies 4-Methoxy-N-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methyl)benzamide (CAS 866018-74-8), a certified reference material (molecular formula C20H17F3N2O2S, MW 406.42 g/mol) for analytical method development and quality control.
The molecular framework of 4-Methoxy-N-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methyl)benzamide (C20H17F3N2O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Methoxy-N-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methyl)benzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H17F3N2O2S |
| Molecular Weight | 406.42 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methoxy Standards
- 4-[(E)-2-(4-Methoxy-3-{4-[(Z)-2-(pyridin-4-yl)ethenyl]phenoxy}phenyl)ethenyl]pyridine (CAS 1171924-43-8)
- 3-(4-Methoxy-2-methylphenyl)-2,5-dimethyl-N-[(S)-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine (CAS 885220-61-1)
- 3-Methoxy-N-[(1-methyl-1H-pyrazol-4-yl)methyl]-N-[2-(pyrrolidin-1-ylsulfonyl)ethyl]benzamide (CAS 1010864-73-9)
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Recommended Standards
- 2-{[4-methyl-5-(3-methylphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-[4-(trifluoromethyl)phenyl]acetamide (CAS 882749-57-7)
- N-(2-methoxybenzyl)-2-(3-(trifluoromethyl)benzyl)thiazole-4-carboxamide (CAS 478042-42-1)
- 2-(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)butanamide (CAS 5840-54-0)
- Ethyl 1-(5-((3-fluorophenyl)carbamoyl)-1,3,4-thiadiazole-2-carbonyl)piperidine-4-carboxylate (CAS 1142210-66-9)
- Tert-butyl 4-(3-(2-nitrophenyl)ureido)piperidine-1-carboxylate (CAS 1197888-17-7)
- (Z)-2-vinylbut-2-enal (CAS CATO-C3D-263009)
- 5-(2-(Methylthio)pyrimidin-4-yl)thiophene-2-sulfonyl chloride (CAS 175202-76-3)
- 4-(Difluoromethoxy)-N-(4h-1,2,4-triazol-3-yl)benzamide (CAS 1050855-05-4)
- (R)-1-(2-Methoxy-4-nitrophenyl)pyrrolidin-3-ol (CAS 851690-75-0)
- (S)-Methyl 2,5-diamino-5-oxopentanoate (CAS 40846-98-8)
- 1-(4-cyclobutylphenyl)-3-(dimethylamino)propan-1-one (CAS 1774520-57-8)
- 2-(Pyridin-3-yl)-6-(trifluoromethyl)benzoic acid (CAS 1214381-12-0)
- 4-(Difluoromethyl)tetrahydro-2H-pyran-4-amine (CAS 1508611-87-7)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
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