(1-Chloronaphtho[2,1-b]thiophen-2-yl)(4-(4-methoxyphenyl)piperazin-1-yl)methanone CAS 866040-32-6

Purity 97%+In StockPharmaceutical Standards
CAS No.866040-32-6
Molecular FormulaC24H21ClN2O2S
Molecular Weight436.95 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(1-Chloronaphtho[2,1-b]thiophen-2-yl)(4-(4-methoxyphenyl)piperazin-1-yl)methanone CAS 866040-32-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 436.95 g/mol gives (1-Chloronaphtho[2,1-b]thiophen-2-yl)(4-(4-methoxyphenyl)piperazin-1-yl)methanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies (1-Chloronaphtho[2,1-b]thiophen-2-yl)(4-(4-methoxyphenyl)piperazin-1-yl)methanone (CAS 866040-32-6), a certified reference material (molecular formula C24H21ClN2O2S, MW 436.95 g/mol) for analytical method development and quality control.

The molecular framework of (1-Chloronaphtho[2,1-b]thiophen-2-yl)(4-(4-methoxyphenyl)piperazin-1-yl)methanone (C24H21ClN2O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC24H21ClN2O2S
Molecular Weight436.95 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms1

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