3-(2-Chlorobenzyl)-6,7-dimethoxy-2-(methylthio)quinazolin-4(3H)-imine CAS 866049-86-7
| CAS No. | 866049-86-7 |
| Molecular Formula | C18H18ClN3O2S |
| Molecular Weight | 375.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 375.87 g/mol gives 3-(2-Chlorobenzyl)-6,7-dimethoxy-2-(methylthio)quinazolin-4(3H)-imine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-(2-Chlorobenzyl)-6,7-dimethoxy-2-(methylthio)quinazolin-4(3H)-imine (CAS 866049-86-7), a certified reference material (molecular formula C18H18ClN3O2S, MW 375.87 g/mol) for analytical method development and quality control.
Structurally, 3-(2-Chlorobenzyl)-6,7-dimethoxy-2-(methylthio)quinazolin-4(3H)-imine (C18H18ClN3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 375.87 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2-Chlorobenzyl)-6,7-dimethoxy-2-(methylthio)quinazolin-4(3H)-imine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18ClN3O2S |
| Molecular Weight | 375.87 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorobenzyl Standards
- 1-(4-Chlorobenzyl)-N-(2-morpholinoethyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 338783-35-0)
- N-(4-(2-((4-Chlorobenzyl)amino)-2-oxoethyl)thiazol-2-yl)furan-2-carboxamide (CAS 857040-22-3)
- 4-(4-(4-Chlorobenzyl)piperazin-1-yl)-3-nitrobenzoic acid (CAS 341967-72-4)
- 2-((4-Chlorobenzyl)sulfinyl)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 339097-86-8)
- 2-Chlorobenzyl (3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)carbamate (CAS 477858-81-4)
- 1-((2-Chlorobenzyl)sulfonyl)-3-(2-chlorophenoxy)propan-2-ol (CAS 478260-53-6)
- 1-(((4-Chlorobenzyl)oxy)methyl)-5-iodopyrimidin-2(1H)-one (CAS 88045-83-4)
- 2-((4-Chlorobenzyl)thio)-3-(thiophen-2-yl)-1,4-diazaspiro[4.5]deca-1,3-diene (CAS 1276469-63-6)
Recommended Standards
- 1-{[6-Chloro-2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-4-carboxylic acid (CAS 893612-77-6)
- 4-(3-chloro-4-methylphenyl)-5-[(4-ethoxyphenoxy)methyl]-4H-1,2,4-triazole-3-thiol (CAS 723332-61-4)
- [1,1'-Biphenyl]-4-yl(2-(4-chlorophenyl)thiazol-5-yl)methanone (CAS 339008-20-7)
- 4-(4-((4-Chlorophenyl)sulfonyl)piperazin-1-yl)-1H-indole (CAS 256458-64-7)
- N,N-Dimethyl-1-((2S,5R)-5-methylmorpholin-2-yl)methanamine (CAS 668434-95-5)
- 1-(2-((Tetrahydrofuran-2-yl)methoxy)ethyl)-1h-pyrazol-3-amine (CAS 1344188-66-4)
- 5-Methyl-3-{[(1E)-3-oxo-3-phenylprop-1-en-1-yl]sulfanyl}-1,2-thiazole-4-carbonitrile (CAS 338953-37-0)
- 3-(2,4-Dichlorobenzyl)-4-hydroxy-1-(3-(methylthio)phenyl)pyridin-2(1H)-one (CAS 672949-08-5)
- 5-(2,4-Difluorophenyl)-1,3,4-thiadiazol-2-amine (CAS 299443-66-6)
- 7-(4-Bromobenzyl)-2-oxa-7-azaspiro[3.5]nonane (CAS 1200131-53-8)
- Hexyl 2-[4-(Diethylamino)-2-hydroxybenzoyl]benzoate (CAS 302776-68-7)
- 6-Chloro-2-fluoro-3-methylphenylboronic Acid (CAS 352535-86-5)
- 6-(Methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-ol (CAS 5334-26-9)
- ([D2]Gly4)-Cholecystokinin Octapeptide (sulfated) ammonium salt (CAS 1926163-74-7)
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