1-{[6-Chloro-2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-4-carboxylic acid CAS 893612-77-6
| CAS No. | 893612-77-6 |
| Molecular Formula | C18H18ClN3O2S |
| Molecular Weight | 375.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-{[6-Chloro-2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-4-carboxylic acid (C18H18ClN3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-{[6-Chloro-2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-4-carboxylic acid (CAS 893612-77-6), molecular formula C18H18ClN3O2S and molecular weight 375.87 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-{[6-Chloro-2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18ClN3O2S |
| Molecular Weight | 375.87 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-(3-chloro-4-methylphenyl)-5-[(4-ethoxyphenoxy)methyl]-4H-1,2,4-triazole-3-thiol (CAS 723332-61-4)
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- 2-[1-(2-Chloro-acetyl)-piperidin-4-ylmethyl]-6-(4-methoxy-phenyl)-2H-pyridazin-3-one (CAS 1229626-96-3)
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- 4-(2-Chloro-6-fluorophenyl)-6-methyl-N-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide (CAS 183231-05-2)
- 2-(1-(3-Chloro-4-morpholinophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-N-methyl-2-oxoacetamide (CAS 860610-29-3)
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Recommended Standards
- [1,1'-Biphenyl]-4-yl(2-(4-chlorophenyl)thiazol-5-yl)methanone (CAS 339008-20-7)
- 3-(2-Chlorobenzyl)-6,7-dimethoxy-2-(methylthio)quinazolin-4(3H)-imine (CAS 866049-86-7)
- Di-tert-butyl (6-chloro-2-(methylthio)pyrimidin-4-yl)iminodicarbonate (CAS 1052714-60-9)
- 2-(4-Chlorophenyl)-3-(4-methylbenzoyl)-1,3-thiazolidine-4-carbohydrazide (CAS 1008281-47-7)
- N-(2-aminoethyl)-4-(tert-butyl)benzamide hydrochloride (CAS 207672-83-1)
- 4-Bromo-7-chloro-1,3-dihydro-2H-benzo[d]imidazole-2-thione (CAS 1388027-75-5)
- 2-(Benzyloxy)-5-hydroxypyridine (CAS 725256-57-5)
- 4-((3S,5R)-3,5-dimethylpiperazin-1-yl)-3-fluoroaniline (CAS 943752-32-7)
- methyl 5,7-dichloropyrazolo[1,5-a]pyrimidine-2-carboxylate (CAS 1211583-00-4)
- N-((1H-Benzo[d]imidazol-1-yl)methyl)-4-nitrobenzamide (CAS 18249-95-1)
- (S)-3-(Methoxymethyl)pyrrolidine (CAS 535924-74-4)
- Methyl 2-chloro-2-(2-(trifluoromethyl)phenyl)acetate (CAS 1250584-13-4)
- 2-(4-Fluoro-5-methoxy-2-nitrophenyl)acetonitrile (CAS 947380-12-3)
- Semaglutide impurity 331 (CAS CATO-C4X-2226231)
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