6-Chloro-4-((2-nitrobenzyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid CAS 866134-66-9
| CAS No. | 866134-66-9 |
| Molecular Formula | C16H13ClN2O7S |
| Molecular Weight | 412.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 6-Chloro-4-((2-nitrobenzyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid (C16H13ClN2O7S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 412.80 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
6-Chloro-4-((2-nitrobenzyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid (CAS 866134-66-9), molecular formula C16H13ClN2O7S and molecular weight 412.80 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloro-4-((2-nitrobenzyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H13ClN2O7S |
| Molecular Weight | 412.80 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-6-[(E)-2-(dimethylamino)ethenyl]-4-oxo-1,4-dihydropyrimidine-5-carbonitrile (CAS 303152-97-8)
- 5-[(2-Chloro-6-fluorophenyl)methyl]-3-(trifluoromethyl)-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxalin-6-one (CAS 1008229-49-9)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-one O-phenylcarbamoyl oxime (CAS 306976-37-4)
- 2-{[5-(6-chloro-3-pyridyl)-4-methyl-4H-1,2,4-triazol-3-yl]thio}-1-[3-(trifluoromethyl)phenyl]ethan-1-one (CAS 680217-47-4)
- (E)-4-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)phenoxy)-1-(dimethylamino)pent-1-en-3-one (CAS 338416-09-4)
- 3'-Chloro-3-[(4-fluorophenyl)methoxy]-2-methyl-5'-(trifluoromethyl)-4H-[1,2'-bipyridine]-4-one (CAS 338965-58-5)
- 1-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-N-(2-fluorobenzyl)pyrrolidine-2-carboxamide (CAS 1008011-41-3)
- 3-(2-Chloro-4-fluorobenzyl)-5-(6-methoxynaphthalen-2-yl)-5-methylimidazolidine-2,4-dione (CAS 956782-57-3)
Recommended Standards
- 2,5-Dibromo-3,4-difluoro-6-iodoaniline (CAS 2750995-89-0)
- 2-(4-Chlorophenyl)-5-methyl-1,3-thiazol-4-yl N-[3-(trifluoromethyl)phenyl]carbamate (CAS 338409-51-1)
- 2,4-Dibromo-6-(difluoromethyl)-3-iodopyridine (CAS 1806839-09-7)
- Imazosulfuron (CAS 122548-33-8)
- Methyl 8-isopropyl-2-methylimidazo[1,2-b]pyridazine-7-carboxylate (CAS 2434602-70-5)
- 2-(N-(4-chlorophenyl)sulfamoyl)acetic acid (CAS 78374-06-8)
- 4-[(4-fluorophenyl)methoxy]piperidine hydrochloride (CAS 1185107-71-4)
- 4-Methoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid (CAS 20923-55-1)
- 3-Acetylthiophene-2-carboxylic acid (CAS 13657-90-4)
- 4-methylthiophen-3-amine hydrochloride (CAS 24030-00-0)
- Oxirane, 2,2'-[1,4-butanediylbis(oxymethylene)]bis-, homopolymer, reaction products with 4,4'-methylenebis[benzenamine] (CAS 68130-85-8)
- 2-Methyl-5-nitro-benzoyl Chloride 2-Methyl-5-nitrobenzoyl Chloride 64688-68-2 (CAS 64688-68-2)
- Boc-D-alanine Hydrate (CAS 75638-15-2)
- Semaglutide impurity 247 (CAS CATO-C4X-2226247)
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