5-[(2-Chloro-6-fluorophenyl)methyl]-3-(trifluoromethyl)-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxalin-6-one CAS 1008229-49-9
| CAS No. | 1008229-49-9 |
| Molecular Formula | C20H17ClF4N2O |
| Molecular Weight | 412.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-[(2-Chloro-6-fluorophenyl)methyl]-3-(trifluoromethyl)-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxalin-6-one.
5-[(2-Chloro-6-fluorophenyl)methyl]-3-(trifluoromethyl)-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxalin-6-one (CAS 1008229-49-9) is a high-purity analytical reference standard with the molecular formula C20H17ClF4N2O and a molecular weight of 412.81 g/mol.
5-[(2-Chloro-6-fluorophenyl)methyl]-3-(trifluoromethyl)-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxalin-6-one (C20H17ClF4N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-[(2-Chloro-6-fluorophenyl)methyl]-3-(trifluoromethyl)-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxalin-6-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H17ClF4N2O |
| Molecular Weight | 412.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-6-[(E)-2-(dimethylamino)ethenyl]-4-oxo-1,4-dihydropyrimidine-5-carbonitrile (CAS 303152-97-8)
- 2-{[5-(6-chloro-3-pyridyl)-4-methyl-4H-1,2,4-triazol-3-yl]thio}-1-[3-(trifluoromethyl)phenyl]ethan-1-one (CAS 680217-47-4)
- 6-Chloro-4-((2-nitrobenzyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid (CAS 866134-66-9)
- (E)-4-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)phenoxy)-1-(dimethylamino)pent-1-en-3-one (CAS 338416-09-4)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-one O-phenylcarbamoyl oxime (CAS 306976-37-4)
- 1-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-N-(2-fluorobenzyl)pyrrolidine-2-carboxamide (CAS 1008011-41-3)
- 3-(2-Chloro-4-fluorobenzyl)-5-(6-methoxynaphthalen-2-yl)-5-methylimidazolidine-2,4-dione (CAS 956782-57-3)
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Recommended Standards
- 2-(4-Chlorophenyl)-5-methyl-1,3-thiazol-4-yl N-[3-(trifluoromethyl)phenyl]carbamate (CAS 338409-51-1)
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- Imazosulfuron (CAS 122548-33-8)
- 2,4-Dibromo-6-(difluoromethyl)-3-iodopyridine (CAS 1806839-09-7)
- 2-(2,5-Dimethoxyphenyl)-4-methylpyrrolidine (CAS 603068-42-4)
- (3R,4R)-4-hydroxy-1-methylpiperidine-3-carboxylic acid (CAS 716362-72-0)
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- 3-Cyclopropoxy-N2,N2,N6,N6-tetramethylpyridine-2,6-diamine (CAS 1243467-78-8)
- Ethyl 3-(2,5-difluorophenoxy)propanoate (CAS 1341783-35-4)
- 4-Amino-6-bromo-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide (CAS 20201-56-3)
- 4-(Methoxycarbonyl)-5-phenylfuran-3-carboxylic acid (CAS 264120-98-1)
- 8-Benzyloxy-N2-isobutyryl-2’-deoxyguanosine (CAS 136859-75-1)
- Palmitoyl Tripeptide-1 HCl (CAS 2757690-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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