1-[2,4-Dichloro-5-(propan-2-yloxy)phenyl]-N-(2,4-dichlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide CAS 866136-32-5
| CAS No. | 866136-32-5 |
| Molecular Formula | C19H16Cl4N4O2 |
| Molecular Weight | 474.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-[2,4-Dichloro-5-(propan-2-yloxy)phenyl]-N-(2,4-dichlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (C19H16Cl4N4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-[2,4-Dichloro-5-(propan-2-yloxy)phenyl]-N-(2,4-dichlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 866136-32-5), molecular formula C19H16Cl4N4O2 and molecular weight 474.17 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H16Cl4N4O2 |
| Molecular Weight | 474.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dichloro Standards
- 1-(2,4-Dichloro-5-isopropoxyphenyl)-N-(3,4-dichlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 400088-28-0)
- 1-[2,4-Dichloro-5-(propan-2-yloxy)phenyl]-N-(2,3-dichlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 400088-27-9)
- 1-[2,4-Dichloro-5-(propan-2-yloxy)phenyl]-N-(2,5-dichlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 866136-31-4)
- 1-[2,4-Dichloro-5-(propan-2-yloxy)phenyl]-N-(3,5-dichlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 400088-30-4)
- 2,3-Dichloro-N-(5,6-dimethyl-1-(3-methylbenzyl)-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338423-40-8)
- 2,4-Dichloro-N-(5,6-dimethyl-1-(2-methylbenzyl)-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338954-84-0)
- 2,4-Dichloro-N-{5,6-dimethyl-1-[(3-methylphenyl)methyl]-1H-1,3-benzodiazol-4-yl}benzene-1-sulfonamide (CAS 338423-46-4)
- 2,5-Dichloro-N-(5,6-dimethyl-1-(2-methylbenzyl)-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338954-81-7)
Recommended Standards
- Zinc bis(diisobutyldithiocarbamate) (CAS 36190-62-2)
- Resmetirom impurity 56 (CAS 3033842-98-4)
- 2,5-Bis(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1,3,4-oxadiazole (CAS 1116122-85-0)
- N'-{6-iodoimidazo[1,2-a]pyridine-2-carbonyl}-4-(trifluoromethyl)benzohydrazide (CAS 860787-45-7)
- 1404194-28-0 4-[Chloro(difluoro)methoxy]-2-fluoro-benzonitrile (CAS 1404194-28-0)
- (1S)-3,3'-Bis(3,5-bis(trifluoromethyl)phenyl)-[1,1'-binaphthalene]-2,2'-disulfonic acid (CAS 1216890-08-2)
- 1-(tert-Butyl) 4-methyl 4-allylpiperidine-1,4-dicarboxylate (CAS 441774-09-0)
- Ethyl 2-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1H-benzo[d]imidazol-1-yl)acetate (CAS 332026-91-2)
- GBR 12909 dihydrochloride, 98% (CAS 67469-78-7)
- N,N'-(3-Cyclopropoxypyridine-2,5-diyl)dimethanesulfonamide (CAS 1243466-56-9)
- 2-(2-Bromobenzyl)morpholine (CAS 1368849-19-7)
- (4-((Methoxymethyl)thio)phenyl)boronic acid (CAS 1072952-17-0)
- 4-(Chloromethyl)-2-phenyl-1,3-thiazole hydrochloride (CAS 79387-14-7)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
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