N-[3-Fluoro-4-(4-phenylpiperazin-1-yl)phenyl]-2-[(4-methylphenyl)sulfanyl]acetamide CAS 866136-80-3
| CAS No. | 866136-80-3 |
| Molecular Formula | C25H26FN3OS |
| Molecular Weight | 435.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies N-[3-Fluoro-4-(4-phenylpiperazin-1-yl)phenyl]-2-[(4-methylphenyl)sulfanyl]acetamide (CAS 866136-80-3), a certified reference material (molecular formula C25H26FN3OS, MW 435.56 g/mol) for analytical method development and quality control.
Based on its molecular formula C25H26FN3OS, N-[3-Fluoro-4-(4-phenylpiperazin-1-yl)phenyl]-2-[(4-methylphenyl)sulfanyl]acetamide contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 435.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H26FN3OS |
| Molecular Weight | 435.56 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- 4-Fluoro-N-(triphenylphosphoranylidene)benzenesulfonamide (CAS 105899-98-7)
- 1-Fluoro-2,3,4,5,6-pentakis(trifluoromethyl)benzene (CAS 81439-39-6)
- 4-(3-Fluoro-4-methylbenzoyl)-1-(furan-2-ylmethyl)-3-hydroxy-5-(4-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 618074-00-3)
- 4-(3-Fluoro-4-methoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 609793-54-6)
- 9α-Fluoro-6α-methylprednisolone 21-Acetate (CAS 432-33-7)
- 4-Fluoro-N-(3-methyl-2,7-dioxo-3,7-dihydro-2H-naphtho[1,2,3-de]quinolin-6-yl)benzenesulfonamide (CAS 670259-16-2)
- 4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-5-(3-hydroxyphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618074-57-0)
- 3-(4-Fluoro-2-nitrophenoxy)-N-(4-sulfamoylphenyl)thiophene-2-carboxamide (CAS 303152-74-1)
Recommended Standards
- N-(2-Fluorophenyl)-4-(2-{[(2-fluorophenyl)carbamothioyl]amino}ethyl)piperazine-1-carbothioamide (CAS 454651-99-1)
- N-Benzyl-2-((5,6-dimethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 332882-86-7)
- N-(2-Ethoxyphenyl)-2-((5-((4-fluorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 477329-04-7)
- Undecyl 9-(2-carbamoylhydrazono)-9H-fluorene-4-carboxylate (CAS 303059-58-7)
- 2,5-Dichloro-3-(difluoromethoxy)benzylamine (CAS 1803714-11-5)
- 4-Hydroxypyrimidine-5-carbonitrile (CAS 4774-34-9)
- Benzyl 3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylate (CAS 65038-89-3)
- 4-(2-Hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile (CAS 338966-41-9)
- 3-Mercaptohexyl Acetate (CAS 136954-20-6)
- N-(3-Chloro-4-fluorophenyl)-2-((5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477330-53-3)
- N,6-Dimethyl-N-(2-(methylamino)-2-oxoethyl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxamide (CAS 1795435-53-8)
- 6-Methyl-2-(thiophene-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid (CAS 315679-26-6)
- 2-[(6-Chloro-2-pyrazinyl)amino]-2-methyl-1-propanol (CAS 1220038-19-6)
- Insulin degludec (CAS 844439-96-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com