4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-5-(3-hydroxyphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one CAS 618074-57-0
| CAS No. | 618074-57-0 |
| Molecular Formula | C24H19FN2O5 |
| Molecular Weight | 434.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-5-(3-hydroxyphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-5-(3-hydroxyphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618074-57-0), a certified reference material (molecular formula C24H19FN2O5, MW 434.42 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-5-(3-hydroxyphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 434.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C24H19FN2O5 |
| Molecular Weight | 434.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 1,3-Dimethyl 5,5-dicyano-4-(4-fluorophenyl)-2-hydroxy-6-phenylcyclohex-1-ene-1,3-dicarboxylate (CAS 1212220-50-2)
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- Cefamandole EP Impurity E (CAS 87932-78-3)
- (3R,4S)-1-Benzyl-4-(3-chlorophenyl)pyrrolidine-3-carboxylic acid (CAS 1394827-71-4)
- N-(1-(2-Hydroxyethyl)-3-(thiophen-2-yl)-1H-pyrazol-5-yl)-5-methylisoxazole-3-carboxamide (CAS 1219901-58-2)
- Boc-L-leucine N-Hydroxysuccinimide Ester (CAS 3392-09-4)
- Propyl 2-amino-4-ethyl-5-methylthiophene-3-carboxylate (CAS 901556-00-1)
- 4-(β-D-Glucopyranosyloxy)-3-(3-methyl-2-buten-1-yl)-benzoic Acid (CAS 23179-40-0)
- 4-Fluoro-3-(methoxymethoxy)-8-((triisopropylsilyl)ethynyl)naphthalen-1-yl trifluoromethanesulfonate (CAS 2856022-37-0)
- 1-Ethyl-4-mercaptoquinolin-2(1H)-one (CAS 437981-37-8)
- 2,3-Dimethyl-2-phenylbutanal (CAS 116936-66-4)
- [2-(tert-butylsulfanyl)pyridin-4-yl]methanamine (CAS 1156217-06-9)
- Polyphemusin II-Derived Peptide (CAS 229030-20-0)
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