1,3-Dimethyl-2,4,5-trioxo-1,2,3,4,5,6-hexahydrofuro[2,3-d]pyrimidine-6-carbaldehyde O-(2,4-dichlorobenzyl)oxime CAS 866137-46-4
| CAS No. | 866137-46-4 |
| Molecular Formula | C16H13Cl2N3O5 |
| Molecular Weight | 398.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1,3-Dimethyl-2,4,5-trioxo-1,2,3,4,5,6-hexahydrofuro[2,3-d]pyrimidine-6-carbaldehyde O-(2,4-dichlorobenzyl)oxime is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1,3-Dimethyl-2,4,5-trioxo-1,2,3,4,5,6-hexahydrofuro[2,3-d]pyrimidine-6-carbaldehyde O-(2,4-dichlorobenzyl)oxime (CAS 866137-46-4), a certified reference material (molecular formula C16H13Cl2N3O5, MW 398.20 g/mol) for analytical method development and quality control.
1,3-Dimethyl-2,4,5-trioxo-1,2,3,4,5,6-hexahydrofuro[2,3-d]pyrimidine-6-carbaldehyde O-(2,4-dichlorobenzyl)oxime (C16H13Cl2N3O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13Cl2N3O5 |
| Molecular Weight | 398.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- 3-Amino-6-(4-bromophenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carbonitrile (CAS 610259-29-5)
- 4-Methylpiperidin-3-ol (CAS 955082-96-9)
- n-(1-(Bicyclo[2.2.1]heptan-2-yl)ethyl)butan-1-amine (CAS 85542-15-0)
- 2,3-Dichloro-4-cyclopropoxypyridine (CAS 1243474-44-3)
- 1-(3-(1,1,2,2-Tetrafluoroethoxy)phenyl)butan-1-ol (CAS 1443346-82-4)
- 2-Chloro-5-(propan-2-yl)benzene-1-sulfonamide (CAS 1195310-17-8)
- 5-(Difluoromethyl)benzo[d]oxazol-2-amine (CAS 1806576-81-7)
- n-(3-Cyanobenzyl)-n,3-dimethylbutanamide (CAS 1197840-07-5)
- 6-(Difluoromethyl)-5-fluoronicotinonitrile (CAS 1805304-99-7)
- 2-((4-Fluorophenyl)thio)-1-(4-hydroxy-3,5-dimethylphenyl)ethan-1-one (CAS 339100-31-1)
- Semaglutide Impurity 130 (CAS 1188328-40-6)
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