N-(4-bromophenyl)-2,2-dicyano-3-(2,4-dichlorophenyl)cyclopropane-1-carboxamide CAS 866137-53-3
| CAS No. | 866137-53-3 |
| Molecular Formula | C18H10BrCl2N3O |
| Molecular Weight | 435.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-bromophenyl)-2,2-dicyano-3-(2,4-dichlorophenyl)cyclopropane-1-carboxamide.
CATO supplies N-(4-bromophenyl)-2,2-dicyano-3-(2,4-dichlorophenyl)cyclopropane-1-carboxamide (CAS 866137-53-3), a certified reference material (molecular formula C18H10BrCl2N3O, MW 435.10 g/mol) for analytical method development and quality control.
Structurally, N-(4-bromophenyl)-2,2-dicyano-3-(2,4-dichlorophenyl)cyclopropane-1-carboxamide (C18H10BrCl2N3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 435.10 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H10BrCl2N3O |
| Molecular Weight | 435.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 1,5-Bis(4-bromophenyl)-2-methyl-1H-pyrrole-3-carboxylic acid (CAS 131721-50-1)
- N-(1-((4-Bromophenyl)sulfonyl)-2,2-dichlorovinyl)benzamide (CAS 867136-34-3)
- 2-((5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-nitrophenyl)acetamide (CAS 332154-87-7)
- 2-((5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(3-nitrophenyl)acetamide (CAS 332114-23-5)
- 2-((5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(4-nitrophenyl)acetamide (CAS 332114-32-6)
- 2-((5-(4-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-nitrophenyl)acetamide (CAS 332162-00-2)
- 2-((5-(4-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(3-nitrophenyl)acetamide (CAS 332161-26-9)
- 2-[(4-Bromophenyl)sulfanyl]-4-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 478245-72-6)
Recommended Standards
- N'-(2,4-Dichlorophenyl)-N-[(1E)-{[(2,6-dichlorophenyl)methoxy]imino}methyl]ethanediamide (CAS 303996-55-6)
- N-(2,4-Dichlorophenyl)-N'-[(1E)-{[(2,4-dichlorophenyl)methoxy]imino}methyl]ethanediamide (CAS 477852-86-1)
- Procymidone Impurity 43 (CAS 169327-83-7)
- 4-{[(2,5-dibromophenyl)sulfonyl]amino}benzoic acid (CAS 735297-59-3)
- (2-Methoxyphenyl)(quinolin-3-yl)methanone (CAS 1182973-82-5)
- 3-Chloro-2-(4,5-dihydro-1H-imidazol-2-yl)-5-(trifluoromethyl)pyridine (CAS 1823183-88-5)
- Ethyl 3-(cyclopentylamino)propanoate (CAS 928788-22-1)
- N5-((R)-3-(((R)-2-((S)-4-amino-4-carboxybutanamido)-2-carboxyethyl)disulfanyl)-1-((carboxymethyl)amino)-1-oxopropan-2-yl)-L-glutamine (CAS 90663-73-3)
- 1-[(1R)-1-chloroethyl]naphthalene (CAS 88766-16-9)
- tert-Butyl 2-methyl-3-(methylamino)-3-oxopropanoate (CAS 2126082-60-6)
- (4-((3,5-Dimethoxybenzyl)oxy)-3,5-dimethylphenyl)boronic acid (CAS 1072951-94-0)
- Methyl 2-amino-5-(4-iodo-1h-pyrazol-1-yl)-2-methylpentanoate (CAS 1341642-19-0)
- 2-Ethoxy-5-iodopyrimidin-4(1H)-one (CAS 222737-72-6)
- Cholecystokinin Octapeptide free acid (desulfated) (H-2075.0001) (CAS 103974-46-5)
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