(E)-[(4-Chlorophenyl)methoxy]({1-[3-(2,2,3,3-tetrafluoropropoxy)-5-(trifluoromethyl)pyridin-2-yl]ethylidene})amine CAS 866137-55-5
| CAS No. | 866137-55-5 |
| Molecular Formula | C18H14ClF7N2O2 |
| Molecular Weight | 458.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-[(4-Chlorophenyl)methoxy]({1-[3-(2,2,3,3-tetrafluoropropoxy)-5-(trifluoromethyl)pyridin-2-yl]ethylidene})amine is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(E)-[(4-Chlorophenyl)methoxy]({1-[3-(2,2,3,3-tetrafluoropropoxy)-5-(trifluoromethyl)pyridin-2-yl]ethylidene})amine (CAS 866137-55-5), molecular formula C18H14ClF7N2O2 and molecular weight 458.76 g/mol, is a CATO reference standard with documented purity and traceability.
(E)-[(4-Chlorophenyl)methoxy]({1-[3-(2,2,3,3-tetrafluoropropoxy)-5-(trifluoromethyl)pyridin-2-yl]ethylidene})amine (C18H14ClF7N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (E)-[(4-Chlorophenyl)methoxy]({1-[3-(2,2,3,3-tetrafluoropropoxy)-5-(trifluoromethyl)pyridin-2-yl]ethylidene})amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14ClF7N2O2 |
| Molecular Weight | 458.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- (2E)-3-{[4-(4-chlorophenyl)-1H-pyrazol-5-yl]amino}-1-[5-(2,4-dichlorophenyl)furan-2-yl]prop-2-en-1-one (CAS 1037690-33-7)
- 6-(4-Chlorophenyl)-4-(trifluoromethyl)-2-{[3-(trifluoromethyl)phenyl]sulfanyl}pyridine-3-carbonitrile (CAS 478049-42-2)
- 3-(4-Chlorophenyl)-4-(2-oxopyridin-1(2H)-yl)-N-(4-(trifluoromethyl)phenyl)-1H-pyrazole-1-carboxamide (CAS 320424-65-5)
- 1-[(3-Chlorophenyl)methyl]-3-methyl-4-[3-(trifluoromethyl)benzoyl]-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 317822-39-2)
- 3-({[(4-chlorophenyl)methyl]sulfanyl}methyl)-5-{[(3,4-dichlorophenyl)methyl]sulfanyl}-4-ethyl-4H-1,2,4-triazole (CAS 344273-55-8)
- 3-{[(4-chlorophenyl)methyl]sulfanyl}-5-({[(2,6-dichlorophenyl)methyl]sulfanyl}methyl)-4-ethyl-4H-1,2,4-triazole (CAS 344270-85-5)
- 5-(3-Chlorophenyl)-2-(4-phenylpiperazin-1-yl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 691873-02-6)
- 4-(4-(4-Chlorophenyl)thiazol-2-yl)-N-(3-(trifluoromethyl)phenyl)benzamide (CAS 338408-10-9)
Recommended Standards
- Didecyl 3,3'-thiodipropanoate (CAS 4275-40-5)
- 2-(2-(2-(DOcosyloxy)ethoxy)ethoxy) ethanol (CAS 297176-96-6)
- Di-tert-butyl (7-bromo-6-chloroquinazolin-2-yl)iminodicarbonate (CAS 2641062-28-2)
- Carnaubadiol (CAS 4547-30-2)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indole (CAS 151387-66-5)
- Methyl 5-benzyloxy-1H-indazole-3-carboxylate (CAS 885278-62-6)
- 2-(4-Methylpiperazin-1-yl)propanoic acid (CAS 938146-50-0)
- 3-Amino-4-chloro-N-ethyl-N-(2-hydroxyethyl)benzenesulfonamide (CAS 1184235-88-8)
- 2-[(Cyclohexylamino)methyl]-5-fluorophenol (CAS 1881322-12-8)
- 5H,8H-imidazo[1,2-b]pyridazin-8-one (CAS 1376761-89-5)
- Methyl 4-Fluoro-3-nitrophenylacetate (CAS 226888-37-5)
- 3-(2,4-Difluorophenyl)-3-acetamidopropanoic acid (CAS 1354962-20-1)
- {2-[(4-Bromophenyl)sulfanyl]-3-pyridinyl}methanol (CAS 338982-33-5)
- Semaglutide Impurity 190 (CAS CATO-C4X-2226190)
Why CATO?
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