2-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}-7-nitro-3,4-dihydro-2H-1,4-benzoxazin-3-one CAS 866137-65-7
| CAS No. | 866137-65-7 |
| Molecular Formula | C21H24N4O5 |
| Molecular Weight | 412.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}-7-nitro-3,4-dihydro-2H-1,4-benzoxazin-3-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}-7-nitro-3,4-dihydro-2H-1,4-benzoxazin-3-one (CAS 866137-65-7) is a high-purity analytical reference standard with the molecular formula C21H24N4O5 and a molecular weight of 412.44 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, 2-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}-7-nitro-3,4-dihydro-2H-1,4-benzoxazin-3-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 412.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C21H24N4O5 |
| Molecular Weight | 412.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
Related methoxyphenyl Standards
- 2-(2-(4-(4-Methoxyphenyl)piperazin-1-yl)ethyl)-6-nitro-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 866133-23-5)
- 4-(2-(4-Methoxyphenyl)-3-methylquinoline-4-carboxamido)benzoic acid (CAS 495377-79-2)
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- (1-((4-Methoxyphenyl)sulfonyl)piperidine-4-carbonyl)-L-leucine (CAS 1212389-18-8)
- 1-[(3-Methoxyphenyl)methyl]-3-{1-[3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl]cyclohexyl}urea (CAS 1396680-11-7)
- 4-[(4-Methoxyphenyl)methyl]-3-[1-(3-methylthiophene-2-carbonyl)piperidin-4-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775544-06-3)
- 3-(1-(4-Methoxyphenyl)-1H-pyrazol-3-yl)-1-(3-(trifluoromethyl)phenyl)pyridazin-4(1H)-one (CAS 318498-03-2)
Recommended Standards
- 2,2'-[1,6-Hexanediylbis(iminocarbonyl)]bis[benzoic acid] (CAS 7177-93-7)
- 2-(4-(4-(Benzyloxy)-6-phenylpyrimidin-2-yl)phenoxy)acetic acid (CAS 651720-01-3)
- 4,4'-((3,3'-Dimethyl-[1,1'-biphenyl]-4,4'-diyl)bis(azanediyl))bis(4-oxobutanoic acid) (CAS 293761-41-8)
- 9,18-Dihydrobenzo[h]benzo[7,8]quino[2,3-b]acridine-7,16-dione (CAS 7520-01-6)
- Chola-3,5-dien-24-oic Acid, Methyl Ester (CAS 1172-10-7)
- (2'-Amino-[1,1'-biphenyl]-4-yl)methanol (CAS 873056-45-2)
- N-Butyl-2-chloronicotinamide (CAS 56149-32-7)
- 328947-93-9 RI376RM5MT LGD-2226 UNII-RI376RM5MT 6-(Bis-(2,2,2-trifluoroethyl)amino)-4-trifluoromethyl-1H-quinolin-2-one (CAS 328947-93-9)
- (R)-4-Ethoxy-2-(methylthio)-6-(pyrrolidin-3-yloxy)pyrimidine hydrochloride (CAS 1353995-17-1)
- Valsartan Impurity 81 (CAS CATO-C4X-105781)
- 2-(tert-Butyl)-1-methyl-1H-benzo[d]imidazole (CAS 178394-77-9)
- 5-(2-(3-Chlorophenyl)benzo[d]oxazol-5-yl)-1,3,4-oxadiazol-2-amine (CAS 1706449-46-8)
- Cefpodoxime Proxetil Impurity 39 (CAS CATO-C4X-157939)
- Insulin Degludec Impurity 6 (CAS CATO-C4X-21576)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com