7-Chloro-6-(2-chloroethyl)-3-(3,4-dimethoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidine CAS 866144-75-4
| CAS No. | 866144-75-4 |
| Molecular Formula | C17H17Cl2N3O2 |
| Molecular Weight | 366.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-Chloro-6-(2-chloroethyl)-3-(3,4-dimethoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidine is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 7-Chloro-6-(2-chloroethyl)-3-(3,4-dimethoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidine (CAS 866144-75-4), a certified reference material (molecular formula C17H17Cl2N3O2, MW 366.24 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 7-Chloro-6-(2-chloroethyl)-3-(3,4-dimethoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 366.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Chloro-6-(2-chloroethyl)-3-(3,4-dimethoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H17Cl2N3O2 |
| Molecular Weight | 366.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 1-Chloro-2-(4-chlorobenzyl)-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile (CAS 459181-43-2)
- 4-Chloro-N-((4-chlorophenyl)sulfonyl)benzenesulfonamide (CAS 2725-55-5)
- (3Z)-6-Chloro-3-[(4-chloro-3-nitrophenyl)methylidene]-3,4-dihydro-2H-1-benzothiopyran-4-one (CAS 900019-21-8)
- 1-Benzyl-3-chloro-3-[(4-chlorophenyl)sulfanyl]pyrrolidine-2,5-dione (CAS 321433-50-5)
- 3-Chloro-N-(5-chloro-2-methoxyphenyl)-6-methylbenzo[b]thiophene-2-carboxamide (CAS 312938-94-6)
- 1-(4-Chloro-phenyl)-3-(6-chloro-4-trifluoromethyl-pyridin-2-yl)-thiourea (CAS 1311279-95-4)
- (1E)-1-(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)-N-(3-chloro-2,4-difluorophenyl)methanimine (CAS 320422-66-0)
- 3-(2-Chloro-6-fluorophenyl)-N-(2-chloropyridin-3-yl)-5-methylisoxazole-4-carboxamide (CAS 368869-90-3)
Recommended Standards
- 6-((3,4-Dichlorophenyl)(pyrrolidin-1-yl)methyl)benzo[d][1,3]dioxol-5-ol (CAS 439110-78-8)
- ethyl 1-(iodomethyl)-3-isopropyl-2-oxabicyclo[2.2.2]octane-4-carboxylate (CAS 2731009-91-7)
- N-(3-acetylphenyl)-4-(2,4-dichlorophenoxy)butanamide (CAS 300825-91-6)
- 3-[(3,5-Dichlorophenyl)amino]-2-phenyl-1H-inden-1-one (CAS 946386-16-9)
- Unsaturated fatty acids, C18, dimers (CAS 61788-89-4)
- 2-(Hydroxyimino)-N-(p-tolyl)acetamide (CAS 1132-40-7)
- N-(2-(3,5-Dimethylphenoxy)ethyl)-4-methylbenzamide (CAS 428847-63-6)
- tert-Butyl 5-fluorospiro[indoline-3,4'-piperidine]-1'-carboxylate (CAS 167484-91-5)
- 2-(3,5-Dimethylphenoxy)-3,3,3-trifluoropropan-1-amine (CAS 886764-07-4)
- 6-Methoxy-3-methyl-1h-indole (CAS 2400-36-4)
- 8-Tosyl-1,4-dioxa-8-azaspiro[4.5]Decane (CAS 853751-19-6)
- 2-oxaspiro[3.5]nonan-7-ol (CAS 2092707-38-3)
- 5-Amino-2-ethyl-7-methylisoindolin-1-one (CAS 1356066-75-5)
- Semaglutide impurity 272 (CAS CATO-C4X-2226272)
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