(3Z)-6-Chloro-3-[(4-chloro-3-nitrophenyl)methylidene]-3,4-dihydro-2H-1-benzothiopyran-4-one CAS 900019-21-8
| CAS No. | 900019-21-8 |
| Molecular Formula | C16H9Cl2NO3S |
| Molecular Weight | 366.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (3Z)-6-Chloro-3-[(4-chloro-3-nitrophenyl)methylidene]-3,4-dihydro-2H-1-benzothiopyran-4-one (C16H9Cl2NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies (3Z)-6-Chloro-3-[(4-chloro-3-nitrophenyl)methylidene]-3,4-dihydro-2H-1-benzothiopyran-4-one (CAS 900019-21-8), a certified reference material (molecular formula C16H9Cl2NO3S, MW 366.22 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (3Z)-6-Chloro-3-[(4-chloro-3-nitrophenyl)methylidene]-3,4-dihydro-2H-1-benzothiopyran-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H9Cl2NO3S |
| Molecular Weight | 366.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Z Standards
- 1-Chloro-2-(4-chlorobenzyl)-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile (CAS 459181-43-2)
- 4-Chloro-N-((4-chlorophenyl)sulfonyl)benzenesulfonamide (CAS 2725-55-5)
- 7-Chloro-6-(2-chloroethyl)-3-(3,4-dimethoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidine (CAS 866144-75-4)
- 1-(4-Chloro-phenyl)-3-(6-chloro-4-trifluoromethyl-pyridin-2-yl)-thiourea (CAS 1311279-95-4)
- (1E)-1-(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)-N-(3-chloro-2,4-difluorophenyl)methanimine (CAS 320422-66-0)
- 1-Benzyl-3-chloro-3-[(4-chlorophenyl)sulfanyl]pyrrolidine-2,5-dione (CAS 321433-50-5)
- 3-Chloro-N-(5-chloro-2-methoxyphenyl)-6-methylbenzo[b]thiophene-2-carboxamide (CAS 312938-94-6)
- 3-(2-Chloro-6-fluorophenyl)-N-(2-chloropyridin-3-yl)-5-methylisoxazole-4-carboxamide (CAS 368869-90-3)
Recommended Standards
- (2R,3R,4R,5R)-2-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-5-((phosphonooxy)methyl)tetrahydrofuran-3-yl acetate (CAS 90290-63-4)
- (5E)-5-{[2-(2,4-dichlorophenoxy)phenyl]methylidene}-1,3-thiazolidine-2,4-dione (CAS 917607-22-8)
- FAICAR ~85% (CAS 13018-54-7)
- 1-((4-Iodophenyl)sulfonyl)-4-methylpiperazine (CAS 914610-38-1)
- (E)-{[2-(4-chlorophenyl)-8-methylimidazo[1,2-a]pyridin-3-yl]methylidene}amino thiophene-2-carboxylate (CAS 478257-08-8)
- 2-(2-Chloro-4-methoxyphenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244084-86-2)
- N1-Benzyl-N1-(4-nitrophenyl)oxalamide (CAS 880150-44-7)
- 2-{(E)-[2-(Diethylamino)-1,3-thiazol-5-yl]methylidene}-1-hydrazinecarbothioamide (CAS 477855-01-9)
- 7-fluoroquinazoline-4-carboxylic acid (CAS 1780977-86-7)
- (Z)-3-Cyclopropyl-5-(thiophen-2-ylmethylene)-2-thioxoimidazolidin-4-one (CAS 1164485-72-6)
- 4-Chloro-2-methylpyrimidine-5-carbaldehyde (CAS 933686-05-6)
- (4-Aminophenyl)boronic acid hydrate (CAS 960355-27-5)
- (<I>R</I>)-<I>N</I>-Boc-1-oxa-4-azaspiro[4.5]decane-3-carboxaldehyde (CAS 171623-07-7)
- Fibrinogen-Binding Inhibitor Peptide (CAS 89105-94-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com