(5E)-2-(4-Methylpiperazin-1-yl)-5-[(naphthalen-1-yl)methylidene]-4,5-dihydro-1,3-thiazol-4-one CAS 866149-73-7
| CAS No. | 866149-73-7 |
| Molecular Formula | C19H19N3OS |
| Molecular Weight | 337.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies (5E)-2-(4-Methylpiperazin-1-yl)-5-[(naphthalen-1-yl)methylidene]-4,5-dihydro-1,3-thiazol-4-one (CAS 866149-73-7), a certified reference material (molecular formula C19H19N3OS, MW 337.44 g/mol) for analytical method development and quality control.
The molecular framework of (5E)-2-(4-Methylpiperazin-1-yl)-5-[(naphthalen-1-yl)methylidene]-4,5-dihydro-1,3-thiazol-4-one (C19H19N3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures (5E)-2-(4-Methylpiperazin-1-yl)-5-[(naphthalen-1-yl)methylidene]-4,5-dihydro-1,3-thiazol-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H19N3OS |
| Molecular Weight | 337.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related E Standards
- 2-(2-(4-Methylpiperazin-1-yl)-2-oxoethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione (CAS 326907-63-5)
- N-(4-Methylpiperazin-1-yl)-5-oxo-4-(thiophen-2-ylmethyl)morpholine-3-carboxamide (CAS 1421444-54-3)
- 3-(2-(4-Methylpiperazin-1-yl)-2-oxoethyl)-7-propyl-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 953254-84-7)
- (2-(4-methylpiperazin-1-yl)-4-phenylchroman-6-yl)methanol (CAS 959624-43-2)
- N-[4-(4-Methylpiperazin-1-yl)phenyl]-2,3-dihydro-1H-indole-1-carboxamide (CAS 685107-70-4)
- 2-(4-methylpiperazin-1-yl)-5-(piperidine-1-sulfonyl)aniline (CAS 901273-43-6)
- N-(2-(4-Methylpiperazin-1-yl)-2-(thiophen-3-yl)ethyl)thiophene-2-carboxamide (CAS 946271-64-3)
- (E)-1-(4-(4-methylpiperazin-1-yl)phenyl)-3-(p-tolylamino)prop-2-en-1-one (CAS 551921-11-0)
Recommended Standards
- (4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(p-tolyl)methanone (CAS 309276-74-2)
- (5Z)-5-{[4-(propan-2-yl)phenyl]methylidene}-3-[(pyridin-3-yl)methyl]-2-sulfanylideneimidazolidin-4-one (CAS 320422-92-2)
- (3-Amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)(3,4-dihydroquinolin-1(2H)-yl)methanone (CAS 692747-83-4)
- 1-(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)-2-phenylethan-1-one (CAS 681158-23-6)
- 4-(4-Bromo-2-fluorophenyl)azetidin-2-one (CAS 1339218-02-8)
- Tert-butyl 4-[2-hydroxy-2-(1-methyl-1h-pyrazol-4-yl)ethyl]piperazine-1-carboxylate dihydrochloride (CAS 1354952-27-4)
- (5E)-5-(3-Chloro-4-hydroxybenzylidene)-2-mercapto-3-phenyl-3,5-dihydro-4H-imidazol-4-one 497835-71-9 (CAS 497835-71-9)
- 5-Amino-2-(hydroxymethyl)benzimidazole (CAS 294656-36-3)
- (Tributylstannyl)methanol (CAS 27490-33-1)
- Ursodeoxycholic Acid Impurity 127 (CAS CATO-C4X-1422127)
- Methyl 5-((3-nitrophenoxy)methyl)furan-2-carboxylate (CAS 832740-50-8)
- N-(5-Formyl-2-hydroxyphenyl)formamide (CAS 903563-43-9)
- 1-(2,4-Dichlorophenyl)-1h-pyrazole-4-carboxylic acid (CAS 1152866-69-7)
- Semaglutide impurity 193 (CAS CATO-C4X-2226193)
Why CATO?
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