4-(4-Fluorobenzyl)-5-(trifluoromethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione CAS 866152-81-0
| CAS No. | 866152-81-0 |
| Molecular Formula | C10H7F4N3S |
| Molecular Weight | 277.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(4-Fluorobenzyl)-5-(trifluoromethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (C10H7F4N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-(4-Fluorobenzyl)-5-(trifluoromethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 866152-81-0) is a high-purity analytical reference standard with the molecular formula C10H7F4N3S and a molecular weight of 277.24 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(4-Fluorobenzyl)-5-(trifluoromethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7F4N3S |
| Molecular Weight | 277.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Fluorobenzyl Standards
- 3-((3-Fluorobenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazole (CAS 1706434-22-1)
- 3-(4-Fluorobenzyl)-1,3,8-triazaspiro[4.5]Decane-2,4-dione (CAS 1092277-64-9)
- 2-Fluorobenzyl 2-(methylthio)nicotinate (CAS 502973-86-6)
- 1242883-08-4 1-(4-Fluorobenzyl)-3-piperidin-4-ylimidazolidin-2-one MFCD15732381 (CAS 1242883-08-4)
- 1242902-54-0 1-(3-Fluorobenzyl)-3-piperidin-4-ylimidazolidin-2-one MFCD15732380 (CAS 1242902-54-0)
- 1-(4-Fluorobenzyl)-4-thioxo-1,3,4,5,6,7-hexahydro-2H-cyclopenta[d]pyrimidin-2-one (CAS 920411-01-4)
- 2-((4-Fluorobenzyl)thio)-1,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one (CAS 451487-18-6)
- Methyl 2-((3-fluorobenzyl)thio)benzoate (CAS 385383-54-0)
Recommended Standards
- 4-(3-Fluoro-5-(trifluoromethyl)phenyl)-2-hydrazinylthiazole (CAS 886504-55-8)
- 4,6-Dimethoxy-N-(2-nitrophenyl)-1,3,5-triazin-2-amine (CAS 27315-30-6)
- 4-(2-Fluoro-4-(trifluoromethyl)phenyl)-2-hydrazinylthiazole (CAS 886505-00-6)
- 5-Isopropyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 436088-40-3)
- 1-(3-Amino-3-(difluoromethyl)azetidin-1-yl)ethan-1-one (CAS 2875097-13-3)
- 5-Phenyl-7-(trifluoromethyl)-2,3-dihydro-1H-1,4-diazepine (CAS 77855-08-4)
- Ethyl-2-amino-4-methoxy-5-(3-morpholin-4-ylpropoxy)benzoate (CAS 1040264-49-0)
- (3S,4R)-4-methylpiperidin-3-ol (CAS 737737-29-0)
- Midazolam Hydrochloride (CAS 59467-96-8)
- Icatibant Impurity 9 (CAS 148416-85-7)
- tert-Butyl N-ethyl-N-(3-hydroxyphenyl)carbamate (CAS 1695391-54-8)
- Ophiopogonoside A (CAS 791849-22-4)
- 5-Methoxy-2-(4-phenyl-1H-pyrazol-3-yl)phenol (CAS 394237-78-6)
- Semaglutide impurity 24 (CAS CATO-C4X-222624)
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