3-(5-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-2-oxo-2,3-dihydro-1,3,4-oxadiazol-3-yl)propanenitrile CAS 866152-91-2
| CAS No. | 866152-91-2 |
| Molecular Formula | C18H13Cl2N3O3 |
| Molecular Weight | 390.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 3-(5-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-2-oxo-2,3-dihydro-1,3,4-oxadiazol-3-yl)propanenitrile (CAS 866152-91-2), a certified reference material (molecular formula C18H13Cl2N3O3, MW 390.22 g/mol) for analytical method development and quality control.
The molecular framework of 3-(5-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-2-oxo-2,3-dihydro-1,3,4-oxadiazol-3-yl)propanenitrile (C18H13Cl2N3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 3-(5-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-2-oxo-2,3-dihydro-1,3,4-oxadiazol-3-yl)propanenitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H13Cl2N3O3 |
| Molecular Weight | 390.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 1-Benzyl-N-(3,5-dichlorophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 338412-50-3)
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- 1-Benzyl-N-(3,4-dichlorophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 338412-54-7)
- Pyridin-3-yl N-{1-[(3,4-dichlorophenyl)methyl]-2-oxo-1,2-dihydropyridin-3-yl}carbamate (CAS 338783-95-2)
- 8-tert-Butyl-4-(4-methyl-3-nitrobenzoyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1326810-10-9)
- (r)-3-Hydroxy-3-phenylpropanoic acid (CAS 2768-42-5)
- 1-(4-Nitro-1h-pyrrole-2-carbonyl)-1,4-diazepan-5-one (CAS 930479-77-9)
- C-(1-Bromo-1-deoxy-2,3,4,6-tetra-O-benzoyl-b-D-glucopyranosyl)formamide (CAS 262849-68-3)
- (Z)-({4-[(4-chlorophenyl)methoxy]-3-methoxyphenyl}methylidene)(methyl)oxidoazanium (CAS 339110-39-3)
- 2-Formyl-6-methylisonicotinonitrile (CAS 448907-01-5)
- Enarodustat Impurity 25 (CAS CATO-C4X-322825)
- 6-Ethoxynaphthalen-1-amine (CAS 837428-13-4)
- (4-(n-(4-Fluorophenyl)sulfamoyl)phenyl)boronic acid (CAS 957121-13-0)
- Palmitoyl hexapeptide-6 (CAS 891498-01-4)
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