N′-(2,5-Difluorophenyl)-N,N-dimethylsulfamide CAS 866154-25-8
| CAS No. | 866154-25-8 |
| Molecular Formula | C8H10F2N2O2S |
| Molecular Weight | 236.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N′-(2,5-Difluorophenyl)-N,N-dimethylsulfamide (CAS 866154-25-8) is a high-purity analytical reference standard with the molecular formula C8H10F2N2O2S and a molecular weight of 236.24 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, N′-(2,5-Difluorophenyl)-N,N-dimethylsulfamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H10F2N2O2S |
| Molecular Weight | 236.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- (S)-1-(3,5-Difluorophenyl)ethyl methanesulfonate (CAS 1076195-98-6)
- 2-[4-(2,6-difluorophenyl)-1,3-thiazol-2-yl]acetonitrile (CAS 184839-29-0)
- [(3,5-Difluorophenyl)sulfamoyl]dimethylamine (CAS 866154-26-9)
- 2-(4-(3,4-Difluorophenyl)thiazol-2-yl)acetonitrile (CAS 883024-06-4)
- N′-(2,4-Difluorophenyl)-N,N-dimethylsulfamide (CAS 349573-48-4)
- N′-(2,6-Difluorophenyl)-N,N-dimethylsulfamide (CAS 866154-28-1)
- (1-(3,4-Difluorophenyl)-2,5-dimethyl-1h-pyrrol-3-yl)methanamine (CAS 1177287-57-8)
- 1-(1-(2,4-Difluorophenyl)-5-methyl-1H-pyrazol-4-yl)ethanone (CAS 105224-00-8)
Recommended Standards
- N-(4-Fluorobenzyl)-2-Oxopyrrolidine-3-Carboxamide (CAS 2007908-57-6)
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- Methyl 3-(5-formylfuran-2-yl)thiophene-2-carboxylate (CAS 255828-29-6)
- trans-2-(4-Fluorobenzoyl)cyclopentane-1-carboxylic acid (CAS 733741-06-5)
- 3-[(Cyclohexylformamido)methyl]benzoic acid (CAS 1184069-53-1)
- 6-(2,4-Dimethylphenyl)pyridazin-3(2H)-one (CAS 4826-92-0)
- 2-chloro-1-oxo-1H-indene-3-carboxylic acid (CAS 75639-84-8)
- Methyl 4-(2-Iodoethyl)benzoate (CAS 1065269-88-6)
- 2-Methylnaphthalene-1-carbonitrile (CAS 20944-85-8)
- 4-(tert-Butyldimethylsilyloxymethyl)bromobenzene (CAS 87736-74-1)
- Choline Chloride (CAS 67-48-1)
- tert-butyl 4-(4-carbamoylphenyl)piperazine-1-carboxylate (CAS 1092481-51-0)
- 3,4,5-Trifluoro-N-propylaniline (CAS 1242882-30-9)
- Acetyl Dipeptide-1 (CAS 196604-48-5)
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