N′-(2,6-Difluorophenyl)-N,N-dimethylsulfamide CAS 866154-28-1
| CAS No. | 866154-28-1 |
| Molecular Formula | C8H10F2N2O2S |
| Molecular Weight | 236.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N′-(2,6-Difluorophenyl)-N,N-dimethylsulfamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies N′-(2,6-Difluorophenyl)-N,N-dimethylsulfamide (CAS 866154-28-1), a certified reference material (molecular formula C8H10F2N2O2S, MW 236.24 g/mol) for analytical method development and quality control.
N′-(2,6-Difluorophenyl)-N,N-dimethylsulfamide (C8H10F2N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N′-(2,6-Difluorophenyl)-N,N-dimethylsulfamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10F2N2O2S |
| Molecular Weight | 236.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- (S)-1-(3,5-Difluorophenyl)ethyl methanesulfonate (CAS 1076195-98-6)
- 2-[4-(2,6-difluorophenyl)-1,3-thiazol-2-yl]acetonitrile (CAS 184839-29-0)
- [(3,5-Difluorophenyl)sulfamoyl]dimethylamine (CAS 866154-26-9)
- 2-(4-(3,4-Difluorophenyl)thiazol-2-yl)acetonitrile (CAS 883024-06-4)
- N′-(2,4-Difluorophenyl)-N,N-dimethylsulfamide (CAS 349573-48-4)
- N′-(2,5-Difluorophenyl)-N,N-dimethylsulfamide (CAS 866154-25-8)
- (1-(3,4-Difluorophenyl)-2,5-dimethyl-1h-pyrrol-3-yl)methanamine (CAS 1177287-57-8)
- 1-(1-(2,4-Difluorophenyl)-5-methyl-1H-pyrazol-4-yl)ethanone (CAS 105224-00-8)
Recommended Standards
- Tert-butyl 5-fluoro-1H-pyrrolo[2,3-b]pyridine-1-carboxylate (CAS 928653-77-4)
- trans-2-(4-Fluorobenzoyl)cyclopentane-1-carboxylic acid (CAS 733741-06-5)
- N-(4-Fluorobenzyl)-2-Oxopyrrolidine-3-Carboxamide (CAS 2007908-57-6)
- Vonoprazan Impurity 271 (CAS CATO-C4X-1020271)
- 4-Chloro-3,5-difluoro-2-methylaniline (CAS 2763538-44-7)
- 914203-36-4 5-Chloro-1-(2-chloropyridin-3-yl)pentan-1-one DTXSID30641809 (CAS 914203-36-4)
- 4-(3-(Trifluoromethyl)phenyl)-1,2,3,6-tetrahydropyridine hydrochloride (CAS 1683-23-4)
- 1-(3,5-Dimethylphenyl)-4,5,6,7-tetrahydro-1h-indazol-4-amine (CAS 1203661-50-0)
- Esmolol Impurity 72 (CAS 1293388-71-2)
- Ethyl 2-(benzylthio)-1,6-dihydropyrimidine-5-carboxylate (CAS 93185-32-1)
- Labetalol EP Impurity G(Mixture of Diastereomers) HCl (CAS CATO-C4X-246634)
- 1043865-63-9 7986AC Amino(pyrazin-2-yl)acetic acid C6H7N3O2 (CAS 1043865-63-9)
- Indometacin Impurity 24 (CAS 99508-25-5)
- Fragment-[3-31]-Semaglutide (CAS CATO-C4X-2226113)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com