(E)-2-Cyano-3-(4-cyanophenyl)-N-[4-(trifluoromethyl)phenyl]-2-propenamide CAS 866156-42-5
| CAS No. | 866156-42-5 |
| Molecular Formula | C18H10F3N3O |
| Molecular Weight | 341.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(E)-2-Cyano-3-(4-cyanophenyl)-N-[4-(trifluoromethyl)phenyl]-2-propenamide (C18H10F3N3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
(E)-2-Cyano-3-(4-cyanophenyl)-N-[4-(trifluoromethyl)phenyl]-2-propenamide (CAS 866156-42-5) is a high-purity analytical reference standard with the molecular formula C18H10F3N3O and a molecular weight of 341.29 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H10F3N3O |
| Molecular Weight | 341.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related E Standards
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Recommended Standards
- 1-[4-(furan-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-4-carboxylic acid (CAS 862712-45-6)
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- 2,2,2-Trifluoro-N-(3-(phenylethynyl)quinoxalin-2-yl)acetamide (CAS 676543-67-2)
- 1-(3-(5-Bromo-2-methylphenoxy)propyl)-4-ethylpiperazine (CAS 1704065-43-9)
- (4-Fluoro-1-naphthalenyl)[1-(5-fluoropentyl)-1H-indol-3-yl]methanone (CAS 1391485-39-4)
- N-(2-Chloro-4-iodophenyl)-4-methylbenzenesulfonamide (CAS 1988004-17-6)
- (4-(Trifluoromethyl)pyridin-3-yl)methanamine dihydrochloride (CAS 1380300-26-4)
- 4-(Hexadecyloxy)-4-oxobutanoic acid (CAS 50893-80-6)
- 6-(Difluoromethoxy)-1H-benzo[d]imidazol-2-amine (CAS 1804172-06-2)
- 2,2-Difluoro-1-(5-methylfuran-2-yl)ethanone (CAS 911193-25-4)
- 2-(3-Bromo-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2057523-47-2)
- 3-(5-Methylthiophen-2-yl)propan-1-amine (CAS 1000530-84-6)
- 3-(4-Methoxyphenyl)-5-methyl-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 878427-26-0)
- Palmitoyl Hexapeptide-12 TFA salt (CAS 171263-26-6(Free Base))
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