5-(4-Fluorobenzyl)-8-methoxy-3-(4-methoxyphenyl)-5H-pyrazolo[4,3-c]quinoline CAS 866347-48-0
| CAS No. | 866347-48-0 |
| Molecular Formula | C25H20FN3O2 |
| Molecular Weight | 413.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-(4-Fluorobenzyl)-8-methoxy-3-(4-methoxyphenyl)-5H-pyrazolo[4,3-c]quinoline (C25H20FN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 5-(4-Fluorobenzyl)-8-methoxy-3-(4-methoxyphenyl)-5H-pyrazolo[4,3-c]quinoline (CAS 866347-48-0), a certified reference material (molecular formula C25H20FN3O2, MW 413.44 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H20FN3O2 |
| Molecular Weight | 413.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorobenzyl Standards
- 5-(2-Fluorobenzyl)-8-methoxy-3-(4-methoxyphenyl)-5H-pyrazolo[4,3-c]quinoline (CAS 866349-45-3)
- 2-((4-Fluorobenzyl)thio)-5-(1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl)-1,3,4-oxadiazole (CAS 478080-24-9)
- 5-((2-Fluorobenzyl)oxy)-2-((4-(furan-2-carbonyl)piperazin-1-yl)methyl)-4H-pyran-4-one (CAS 898440-23-8)
- 5-((3-Fluorobenzyl)oxy)-2-((4-(furan-2-carbonyl)piperazin-1-yl)methyl)-4H-pyran-4-one (CAS 898420-94-5)
- 4-(4-Fluorobenzyl)-3-((4-nitrobenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazole (CAS 294853-30-8)
- 5-(4-((3-Fluorobenzyl)oxy)-3-iodophenyl)-1,3,4-oxadiazol-2-amine (CAS 1706448-66-9)
- 4-((1-(3-Fluorobenzyl)-1H-indazol-5-yl)amino)-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid (CAS 856667-80-6)
- 2-((2-Fluorobenzyl)thio)-5-(4-(2-methoxyphenyl)piperazin-1-yl)-1,3,4-thiadiazole (CAS 1105222-96-5)
Recommended Standards
- Piperidine Impurity 1 (CAS 1463453-46-4)
- 4-Phenyl-2-(2-(pyrrolidin-1-yl)ethyl)-6-(3-(trifluoromethyl)phenyl)pyridazin-3(2H)-one (CAS 23419-43-4)
- Letermovir impurity 137 (CAS CATO-C4X-2915137)
- 4-Methyl-N-(7-(5-methylfuran-2-carbonyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzenesulfonamide (CAS 886493-73-8)
- 3-(Chloromethyl)-5-methylpyridazine (CAS 1956325-05-5)
- 3-Methoxy-4-{[(4-methoxyphenyl)carbamoyl]methoxy}benzoic acid (CAS 750613-33-3)
- 2-azabicyclo[3.1.1]heptane-1-carboxylic acid hydrochloride (CAS 1172802-41-3)
- 9-Chloro-1-methyl-1,10-phenanthrolin-2(1H)-one (CAS 29176-54-3)
- 3-(4-Bromo-2-fluorophenoxy)azetidine hydrochloride (CAS 1713160-68-9)
- tert-butyl (2S)-2-formylpiperidine-1-carboxylate (CAS 150521-32-7)
- Gadoterate Meglumine (CAS 92943-93-6)
- 7-Ethylquinoline-2,3-dicarboxylic acid (CAS 948290-58-2)
- N-butyl-N-phenylacetamide (CAS 91-49-6)
- Tirzepatide Impurity 19 X TFA Salt (CAS CATO-C4X-324019)
Why CATO?
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