1-(2-Fluorophenyl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one CAS 866472-46-0
| CAS No. | 866472-46-0 |
| Molecular Formula | C10H9FN2O |
| Molecular Weight | 192.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 192.19 g/mol gives 1-(2-Fluorophenyl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-(2-Fluorophenyl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one (CAS 866472-46-0), a certified reference material (molecular formula C10H9FN2O, MW 192.19 g/mol) for analytical method development and quality control.
The molecular framework of 1-(2-Fluorophenyl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one (C10H9FN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9FN2O |
| Molecular Weight | 192.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- 1-(4-Fluorophenyl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one (CAS 100553-83-1)
- (3-(4-Fluorophenyl)-1h-pyrazol-4-yl)methanol (CAS 1017783-51-5)
- (5-(4-Fluorophenyl)isoxazol-3-yl)methanamine (CAS 1018604-92-6)
- [3-(3-fluorophenyl)-1,2-oxazol-5-yl]methanamine (CAS 1033693-12-7)
- 1-(2-fluorophenyl)-3-prop-2-yn-1-ylurea (CAS 1090922-05-6)
- (3-(4-Fluorophenyl)-1h-pyrazol-5-yl)methanol (CAS 1137165-21-9)
- [1-(4-fluorophenyl)-1h-pyrazol-3-yl]methanol (CAS 1202942-29-7)
- 1-(4-Fluorophenyl)-1H-pyrazole-3,5-diamine (CAS 1248501-80-5)
Recommended Standards
- 1-(2-fluorobenzyl)-1H-1,2,4-triazol-3-amine (CAS 832740-23-5)
- 1-(3-Fluorophenyl)-3-methyl-4,5-dihydro-1H-pyrazol-5-one (CAS 20124-84-9)
- [5-(2-Fluorophenyl)-2-furyl]methanol (CAS 637728-08-6)
- 1-(4-acetylphenyl)-2-fluoroprop-2-en-1-one (CAS 506437-39-4)
- Tert-butyl (1-(4-methoxybenzoyl)piperidin-4-yl)carbamate (CAS 1261009-88-4)
- 4-([1,1'-Biphenyl]-4-yl)-2-(pyridin-3-yl)thiazole (CAS 70031-92-4)
- Isofagomine D-Tartrate (CAS 957230-65-8)
- tert-Butyl (3-((2-amino-4-methylphenyl)amino)propyl)carbamate (CAS 1697938-36-5)
- 1-(6,7-Dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidin-3-yl)methanamine (CAS 342402-81-7)
- 6-Chlorocinnolin-3(2H)-one (CAS 101495-52-7)
- 593255-20-0 2-Iodo-1,5-dimethyl-3-nitrobenzene DTXSID20556039 (CAS 593255-20-0)
- Abemaciclib Impurity 10 (CAS CATO-C4X-293710)
- N-Isobutyl-4-methoxybenzenesulfonamide (CAS 172738-60-2)
- β-Bag Cell Peptide (Aplysia californica) (CAS 109024-47-7)
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