1-(4-Fluorophenyl)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one CAS 866472-48-2
| CAS No. | 866472-48-2 |
| Molecular Formula | C10H6F4N2O |
| Molecular Weight | 246.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 1-(4-Fluorophenyl)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one (C10H6F4N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 246.16 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-(4-Fluorophenyl)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 866472-48-2), molecular formula C10H6F4N2O and molecular weight 246.16 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(4-Fluorophenyl)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6F4N2O |
| Molecular Weight | 246.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- 1-(2-Fluorophenyl)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 1152564-84-5)
- 1-(3-Fluorophenyl)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 866472-60-8)
- 1-(4-Fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-5-ol (CAS 854678-00-5)
- 2-(4-Fluorophenyl)-4-methyl-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile (CAS 478048-47-4)
- N5-(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine (CAS 294873-69-1)
- 2-((4-Fluorophenyl)ethynyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1005000-16-7)
- 2-(5-(2-Fluorophenyl)furan-2-yl)cyclopropanecarboxylic acid (CAS 1315372-59-8)
- 2-(5-(4-Fluorophenyl)furan-2-yl)cyclopropanecarboxylic acid (CAS 1315374-05-0)
Recommended Standards
- 2-(1,2,2,2-Tetrafluoroethyl)quinazolin-4(1H)-one (CAS 63099-85-4)
- Diethyl 2,2,3,3-tetrafluorosuccinate (CAS 377-71-9)
- 4-Methyl-5-oxo-2,5-dihydrofuran-3-yl trifluoromethanesulfonate (CAS 157123-02-9)
- 2,5-Bis(trifluoromethyl)benzenethiol (CAS 1028328-58-6)
- 1-(Methyl-d3)-piperazine hydrochloride (CAS 1093380-08-5)
- 3-(5-Fluoro-2-methylphenyl)-2-methyl-1-propene (CAS 951894-69-2)
- tert-Butyl 4-({2'-[(Z)-N'-Hydroxycarbamimidoyl]-[1,1'-biphenyl]-4-yl}methyl)piperazine-1-carboxylate (CAS 1253528-84-5)
- (2S,3R,4S,5R,6R)-6-((trityloxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (CAS 37074-90-1)
- trans-Methyl 2,2-dimethyl-3-hydroxycyclobutanecarboxylate (CAS 1392804-78-2)
- tert-Butyl 4-(2-(4-bromophenoxy)acetyl)piperazine-1-carboxylate, 97% (CAS 1147343-55-2)
- 5,8-Dimethoxychroman-4-one (CAS 854843-02-0)
- 4-Bromo-2-(difluoromethyl)-6-methoxypyridine (CAS 1804440-92-3)
- 2,7-Dimethyl-6-(1H-pyrazol-3-yl)[1,2,4]triazolo[1,5-a]pyrimidine (CAS 1428139-39-2)
- Semaglutide impurity 249 (CAS CATO-C4X-2226249)
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