N-(3-Methoxy-phenyl)-malonamic acid ethyl ester CAS 86648-53-5
| CAS No. | 86648-53-5 |
| Molecular Formula | C12H15NO4 |
| Molecular Weight | 237.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(3-Methoxy-phenyl)-malonamic acid ethyl ester (CAS 86648-53-5), molecular formula C12H15NO4 and molecular weight 237.25 g/mol, is a CATO reference standard with documented purity and traceability.
N-(3-Methoxy-phenyl)-malonamic acid ethyl ester (C12H15NO4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15NO4 |
| Molecular Weight | 237.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 1 |
Related N Standards
- 4-(3-Methoxy-phenyl)-morpholine-2-carboxylic acid (CAS 1316220-58-2)
- 4-methoxy-5-sulfamoylthiophene-2-carboxylic acid (CAS 1384429-01-9)
- Methyl 8-methoxy-6-oxo-2,3,4,6-tetrahydro-1H-quinolizine-9-carboxylate (CAS 1638612-50-6)
- N-Methoxy-N-methyl-2-phenyl-isobutyramide (CAS 169280-16-4)
- 2-Methoxy-4-(2-nitrovinyl)-1-propoxybenzene (CAS 70622-82-1)
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- 2-Methoxy-5-morpholinobenzoic acid (CAS 825619-47-4)
- 4-(2-Methoxy-benzoylamino)-butyric acid (CAS 257952-11-7)
Recommended Standards
- N-(2-Methoxy-phenyl)-malonamic acid ethyl ester (CAS 90475-72-2)
- N-(6-Fluoro-2-pyridinyl)-2-thiophenecarbohydrazide (CAS 338780-86-2)
- Methyl2-hydroxy-4-morpholinobenzoate (CAS 207850-94-0)
- N-(9-Oxo-9H-fluoren-2-yl)acetamide (CAS 3096-50-2)
- Pyridine-2,4-dicarbaldehyde hydrate (CAS 1071565-78-0)
- (R)-1-Phenyl-2-(p-tolyl)ethylamine (CAS 30339-32-3)
- tert-Butyl N-[(1-aminocyclohexyl)methyl]carbamate hydrochloride (CAS 2306278-10-2)
- Fosaprepitant Impurity 41 (CAS 287930-73-8)
- 1-(Cyclopropylmethyl)-3,5-diphenyl-1H-benzo[d]imidazol-2(3H)-one (CAS 1359758-29-4)
- N-(2-Oxo-1,2-dihydropyrimidin-4-yl)isobutyramide (CAS 97626-98-7)
- 2-(4-Bromophenoxy)propanehydrazide (CAS 325778-59-4)
- Methyl 5-((5-(3-methyl-1,2,4-oxadiazol-5-yl)-2-oxopyridin-1(2H)-yl)methyl)furan-2-carboxylate (CAS 1396765-40-4)
- Tadalafil Impurity 174 (CAS CATO-C4X-1087174)
- Palmitoyl Tripeptide-1 HCl (CAS 2757690-14-3)
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