Ticagrelor Impurity 142 CAS 866551-95-3
| CAS No. | 866551-95-3 |
| Molecular Formula | C20H27NO7 |
| Molecular Weight | 393.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ticagrelor Impurity 142 (C20H27NO7) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Ticagrelor Impurity 142 (CAS 866551-95-3) is a certified pharmaceutical impurity reference standard with the molecular formula C20H27NO7 and a molecular weight of 393.43 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ticagrelor Impurity 142 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H27NO7 |
| Molecular Weight | 393.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity 11 (CAS 2248538-63-6)
- Ticagrelor Impurity 93 (CAS CATO-C4X-109393)
- Ticagrelor Impurity 109 (CAS CATO-C4X-1093109)
- Ticagrelor Impurity 74 (CAS 220241-61-2)
- Ticagrelor Impurity 67 (CAS CATO-C4X-109367)
- Ticagrelor Impurity 111 (CAS 220352-29-4)
- Ticagrelor impurity 169 (CAS CATO-C4X-1093169)
- Ticagrelor Impurity 144 (CAS CATO-C4X-1093144)
Recommended Standards
- Z-Gly-Leu-Ala-OH (C-3260.0250) (CAS 24960-20-1)
- Ezetimibe Impurity 1 (CAS 204589-58-2)
- Phenolphthalein anilide (CAS 6607-41-6)
- Metaraminol Impurity 65 (CAS 31301-86-7)
- Safinamide Impurity 25 (CAS CATO-C4X-159025)
- Ceftezole Impurity 3 (CAS CATO-C4X-23093)
- Deferiprone EP Impurity C (CAS CATO-C4X-30487)
- 1-(2,4-Difluorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione (CAS 6954-65-0)
- Cnidioside B methyl ester (CAS 158500-59-5)
- 2-(4-(2-Amino-3-cyano-5-oxo-5,6,7,8-tetrahydro-4H-chromen-4-yl)-2-methoxyphenoxy)-N-(3-chlorophenyl)acetamide (CAS 352435-87-1)
- 5-(3-Chloro-4-fluorophenyl)pyridin-2-amine (CAS 1314985-70-0)
- 7-Hydroxy-3,4,6-trimethyl-2,3-dihydro-1H-inden-1-one (CAS 19723-30-9)
- (2-Amino-5,6-dihydro-4H-cyclopenta[b]thiophen-3-yl)-p-tolyl-methanone (CAS 436093-41-3)
- (Cys2)-Neuropeptide Y-8-aminooctanoyl-(D-Cys27)-Neuropeptide Y (25-32) (H-3298.0500) (CAS 128806-04-2)
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