Tepotinib impurity 11 CAS CATO-C4X-337411
| CAS No. | CATO-C4X-337411 |
| Molecular Formula | C22H14BrN5O |
| Molecular Weight | 444.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Tepotinib impurity 11 (CAS CATO-C4X-337411), a pharmacopoeial impurity reference standard (molecular formula C22H14BrN5O, MW 444.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Tepotinib impurity 11 (C22H14BrN5O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Tepotinib impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H14BrN5O |
| Molecular Weight | 444.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
Related Tepotinib Standards
- Tepotinib impurity 12 (CAS CATO-C4X-337412)
- Tepotinib impurity 13 (CAS CATO-C4X-337413)
- Tepotinib impurity 27 (CAS CATO-C4X-337427)
- Tepotinib impurity 3 (CAS 1103506-82-6)
- Tepotinib impurity 16 (CAS CATO-C4X-337416)
- Tepotinib impurity 21 (CAS CATO-C4X-337421)
- Tepotinib impurity 23 (CAS CATO-C4X-337423)
- Tepotinib impurity 18 (CAS CATO-C4X-337418)
Recommended Standards
- 2-(((6-Bromo-4-oxoquinazolin-3(4H)-yl)methyl)amino)-N-(o-tolylcarbamoyl)acetamide (CAS 86816-92-4)
- 2-((4-Allyl-5-(((4-iodophenyl)amino)methyl)-4H-1,2,4-triazol-3-yl)thio)acetohydrazide (CAS 1306738-91-9)
- (E)-1-(3-(3,4-Bis(trifluoromethoxy)phenyl)acryloyl)quinazolin-4(1H)-one (CAS 1295538-24-7)
- 2-Iodo-N-(1-methylnaphtho[1,2-d]thiazol-2(1H)-ylidene)benzamide (CAS 477501-13-6)
- Propranolol Impurity 63 (CAS CATO-C4X-151963)
- Estradiol Impurity 20 (CAS 2398-63-2)
- Tofacitinib Impurity 58 (CAS CATO-C4X-107958)
- (Hydroxymethyl)triphenylphosphonium chloride (CAS 5293-83-4)
- (3-Chlorophenyl)methyl acetate (CAS 21388-93-2)
- (1-(4-Fluorophenyl)-3,5-dimethyl-1H-pyrazol-4-yl)methanamine hydrochloride (CAS 1255717-06-6)
- 5-methyl-N-(propan-2-yl)-4H-1,2,4-triazol-3-amine (CAS 1803600-04-5)
- Octadecylbenzene (CAS 4445-07-2)
- 6-Chloro-3-isopropyl-5-methylpyrimidine-2,4(1H,3H)-dione (CAS 1567026-03-2)
- Renin Inhibitor Peptide (CAS 50410-01-0)
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