1-(Methylsulfonyl)-2-((4-(trifluoromethyl)benzyl)thio)-4,5-dihydro-1H-imidazole CAS 868218-23-9
| CAS No. | 868218-23-9 |
| Molecular Formula | C12H13F3N2O2S2 |
| Molecular Weight | 338.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(Methylsulfonyl)-2-((4-(trifluoromethyl)benzyl)thio)-4,5-dihydro-1H-imidazole (C12H13F3N2O2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 1-(Methylsulfonyl)-2-((4-(trifluoromethyl)benzyl)thio)-4,5-dihydro-1H-imidazole (CAS 868218-23-9), a certified reference material (molecular formula C12H13F3N2O2S2, MW 338.37 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(Methylsulfonyl)-2-((4-(trifluoromethyl)benzyl)thio)-4,5-dihydro-1H-imidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13F3N2O2S2 |
| Molecular Weight | 338.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Methylsulfonyl Standards
- 1-(Methylsulfonyl)-2-((3-(trifluoromethyl)benzyl)thio)-4,5-dihydro-1H-imidazole (CAS 868218-11-5)
- 5-(Methylsulfonyl)-4-(4-nitrophenyl)-1H-thieno[2,3-c]pyrazol-3-amine (CAS 1707379-13-2)
- N-((1-(Methylsulfonyl)piperidin-4-yl)methyl)-4-propylbenzamide (CAS 1234842-42-2)
- 5-(Methylsulfonyl)-2-(trifluoromethoxy)benzene-1-sulfonyl chloride (CAS 1349716-91-1)
- 2-((4-(Methylsulfonyl)piperazin-1-yl)methyl)-4-phenylthiazole (CAS 1105216-21-4)
- N-(5-(Methylsulfonyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)pyrazine-2-carboxamide (CAS 1396707-93-9)
- 2-((4-(Methylsulfonyl)phenyl)amino)-N-propylthiazole-4-carboxamide (CAS 1210495-41-2)
- 2,4-Bis(methylsulfonyl)-6-phenylnicotinonitrile (CAS 84671-65-8)
Recommended Standards
- 1-(tert-Butoxycarbonyl)-4-((3-fluorophenyl)amino)piperidine-4-carboxylic acid (CAS 2177267-34-2)
- (1S,2S,3R,4S)-Diethyl 3-(4-fluorophenyl)-4-hydroxycyclohexane-1,2-dicarboxylate (CAS 860642-64-4)
- 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(3-fluorophenyl)acetic acid (CAS 885272-91-3)
- ((3AR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-yl)methyl methanesulfonate (CAS 4148-55-4)
- 2-Butoxy-5-methylpyridine-3-boronic acid (CAS 2096330-20-8)
- 2-Pyridin-2-ylquinoline-4-carbonyl chloridehydrochloride (CAS 1332528-97-8)
- 2-(Carboxymethyl)-3-oxopyrrolidine-1-carboxylic acid (CAS 857205-87-9)
- 2-((3-(4-Fluorophenyl)quinolin-2-yl)oxy)-N,N-dimethylethanamine (CAS 89111-00-2)
- 2-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)propanal (CAS 23101-87-3)
- 4-(3-Chloro-4-methylphenyl)piperidine (CAS 899359-30-9)
- 2-(2-Fluoro-3-phenylbicyclo[1.1.1]pentan-1-yl)propanoic acid (CAS 2742656-74-0)
- 1-(2,3,5,6-Tetrafluorobenzyl)-1H-pyrazol-4-amine (CAS 1005630-54-5)
- Lercanidipine Impurity 21 HCl (CAS 210579-71-8)
- Gastric Inhibitory Polypeptide (1-30) amide (porcine) (CAS 134846-93-8)
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