2-((4-Amino-6-methyl-5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)thio)-N-(4-fluorophenyl)acetamide CAS 869067-65-2
| CAS No. | 869067-65-2 |
| Molecular Formula | C12H12FN5O2S |
| Molecular Weight | 309.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((4-Amino-6-methyl-5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)thio)-N-(4-fluorophenyl)acetamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-((4-Amino-6-methyl-5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)thio)-N-(4-fluorophenyl)acetamide (CAS 869067-65-2), a certified reference material (molecular formula C12H12FN5O2S, MW 309.32 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 2-((4-Amino-6-methyl-5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)thio)-N-(4-fluorophenyl)acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 309.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-((4-Amino-6-methyl-5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)thio)-N-(4-fluorophenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12FN5O2S |
| Molecular Weight | 309.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 2-(4-(4-Amino-2-methoxy-5-oxo-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)phenyl)acetonitrile (CAS 1956326-85-4)
- 2-((4-Amino-6-methyl-5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)thio)-N-(2-fluorophenyl)acetamide (CAS 869067-63-0)
- 2-((4-Amino-6-methyl-5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)thio)-N-(3-fluorophenyl)acetamide (CAS 869067-64-1)
- 5-Amino-N-(2-methoxyphenyl)-1-phenyl-1H-1,2,3-triazole-4-carboxamide (CAS 950248-65-4)
- 6-Amino-5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carbonyl)-2,3-dihydro-1H-pyrrolizine-7-carbonitrile (CAS 924858-84-4)
- Ethyl 1-(4-amino-1,2,5-oxadiazol-3-yl)-5-((diethylamino)methyl)-1H-1,2,3-triazole-4-carboxylate (CAS 311321-80-9)
- 2-(Boc-amino)-1-(2,5-difluorophenyl)-4-pentyn-1-one (CAS 1172623-96-9)
- 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 1224844-38-5)
Recommended Standards
- 2-(2,4-Dimethoxyphenyl)quinoline-4-carboxylic acid (CAS 313704-08-4)
- 2-(2,5-Dimethoxyphenyl)quinoline-4-carboxylic acid (CAS 485335-52-2)
- 2-((1-Phenyl-4,5-dihydro-1H-pyrazol-3-yl)carbamoyl)benzoic acid (CAS 304661-57-2)
- 2-(2-Ethoxyphenyl)-4-oxo-1,4-dihydroquinoline-6-carboxylic acid (CAS 90034-42-7)
- 285979-75-1 D-(C~6~,C~6~-~2~H_2_)Fructofuranose DTXSID20746034 (CAS 285979-75-1)
- Carbetocin Sulfoxide (CAS CATO-C4X-191118)
- 1,5-Dichloro-9,10-diphenylanthracene (CAS 80034-46-4)
- 4-Chlorophenyl 2-(4-methoxyphenyl)quinoline-4-carboxylate (CAS 332381-14-3)
- 2-(2-(2,6-Dichlorophenoxy)ethyl)-1,3-dioxolane (CAS 1226306-16-6)
- 3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-1-(p-tolyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-94-5)
- 7-Methoxyquinolin-8-amine (CAS 83010-84-8)
- 4-Bromo-5-methyl-1h-pyrrole-2-carbaldehyde (CAS 52115-67-0)
- Efavirenz Related Compound A (CAS 209414-27-7)
- ([D2]Gly4)-Cholecystokinin Octapeptide (sulfated) ammonium salt (CAS 1926163-74-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com