Lacosamide EP Impurity K CAS 86921-49-5
| CAS No. | 86921-49-5 |
| Molecular Formula | C12H14N2O2 |
| Molecular Weight | 218.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Lacosamide EP Impurity K (CAS 86921-49-5), a pharmacopoeial impurity reference standard (molecular formula C12H14N2O2, MW 218.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C12H14N2O2, Lacosamide EP Impurity K contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 218.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lacosamide EP Impurity K meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14N2O2 |
| Molecular Weight | 218.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 2 |
Related Lacosamide Standards
- Lacosamide Impurity 29 (CAS 86123-95-7)
- Lacosamide Impurity 31 (CAS 93782-09-3)
- Lacosamide Impurity 34 (CAS 86921-48-4)
- Lacosamide Impurity 50 (CAS 2295925-92-5)
- Lacosamide Impurity 53 (CAS CATO-C4X-183053)
- Lacosamide EP Impurity D (R-isomer) (CAS 196601-69-1)
- Lacosamide EP Impurity D (CAS 262845-82-9)
- Lacosamide Impurity 51 (CAS CATO-C4X-183051)
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com