7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid CAS 869947-41-1
| CAS No. | 869947-41-1 |
| Molecular Formula | C8H4F3N3O2 |
| Molecular Weight | 231.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 869947-41-1), molecular formula C8H4F3N3O2 and molecular weight 231.13 g/mol, is a CATO reference standard with documented purity and traceability.
7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (C8H4F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4F3N3O2 |
| Molecular Weight | 231.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 2-(Trifluoromethyl)-1,3-benzoxazole-6-carboxylic acid (CAS 1181288-08-3)
- 6-(Trifluoromethyl)-2,1-benzoxazole-3-carboxylic acid (CAS 1204298-47-4)
- 8-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine-3-carboxylic acid (CAS 1210246-41-5)
- 7-(Trifluoromethyl)imidazo[1,2-a]pyrimidine-6-carboxylic acid (CAS 1260847-63-9)
- 6-(Trifluoromethyl)imidazo[1,2-a]pyrazine-2-carboxylic acid (CAS 1372197-49-3)
- 5-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)pyrimidin-2-amine (CAS 1433206-24-6)
- 5-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)pyrazin-2-amine (CAS 1441875-37-1)
- 2-(trifluoromethyl)-1,3-benzoxazole-5-carboxylic acid (CAS 1495165-30-4)
Recommended Standards
- 7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 869947-40-0)
- 8-(Trifluoromethyl)-1h-benzo[d][1,3]oxazine-2,4-dione (CAS 72985-50-3)
- 7-(Trifluoromethyl)-1H-benzo[d][1,3]oxazine-2,4-dione (CAS 97928-01-3)
- 32281-97-3 7-BROMO-2,3,4-TRIHYDRONAPHTHALEN-1-ONE 7-BROMO-3,4-DIHYDRO-1(2H)-NAPHTHALENONE 7-BROMO-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE 7-BROMO-ALPHA-TETRALONE 7-BROMOTETRALONE BC004082 (CAS 32281-97-3)
- 1,3-Bis(4-bromophenyl)-1H-pyrazol-5-amine (CAS 618098-21-8)
- 1-(1-Phenylvinyl)-1H-benzo[d]imidazol-2(3H)-one (CAS 60739-31-3)
- Ethyl 2-(2-cyanoethyl)-3-oxooctanoate (CAS 872804-89-2)
- 2-(2-Chloro-6-fluorophenyl)-2-fluoroacetic acid (CAS 1556900-34-5)
- 1-Methyl-6-nitronaphthalene (CAS 105752-67-8)
- 5-(Bromomethyl)-2-fluoropyridine hydrobromide (CAS 31140-61-1)
- 4-(Bromomethyl)cyclohexane-1-carbonitrile (CAS 62221-23-2)
- Tetrakis(triphenylphosphine)nickel(0) (CAS 15133-82-1)
- (1H-imidazol-1-yl)(2,3,5-triiodophenyl)methanone (CAS CATO-C3D-262281)
- Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 2022956-56-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com